Protein Alignment Rexo5 and panl-2

DIOPT Version :10

• Sequence 1: NP_648050.1
• Gene: Rexo5 / 38740
• FlyBaseID: FBgn0286051
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_498519.1
• Gene: panl-2 / 175974
• WormBaseID: WBGene00017951
• Length: 1131
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 121/558 - (21%)
• Similarity: 204/558 - (36%)
• Gaps: 161/558 - (28%)

  Fly   110 GGDSLPLEIGSLSEDQYNQLS-AELRRRKRELENVPALRL--------------REM-------- 151
            |.||     |.:..:...|:| .|.:|:.|||.  |.|.:              |::
 Worm   645 GDDS-----GEIECEDCKQMSRMECKRKVRELS--PVLLIDTNASSNGFVEFWRRQLSLFERKPG 702

  Fly   152 GQRASL-----ETPQDARTPIFLTDIQNLLMCALIGQKSPCRPDRWCSVEKWLSLSHSVV----- 206
            |.|:|.     |:|.:.:...|.||.:|...|..:                     |.:|
 Worm   703 GNRSSALGTVPESPSEKKNCRFGTDCRNKKTCKFV---------------------HGLVDWPAE 746

  Fly   207 --VILEGLSL---YHYLSNETQFEATNRIFSTKLEMILPPQEEGQKIIDEIAKI----------- 255
              .:||.:.|   .||:.:....:....|........||..:|...:|.|:..:
 Worm   747 QTKLLEDVDLPEWAHYIPSRIAAQLCEGIVRLSDVSDLPDYDEPSAVIYELDAMIHAVGNGENDV 811

  Fly   256 ----PLTNAQARRLIDEHGSL--ESAVELNKD------------PTL--FVKTIFPIESSKSESD 300
                |:|..:...:|....:|  |..|....|            |.|  :.|..|.:::    |:
 Worm   812 NWTHPVTLLRESPVISSSWTLINEQLVSRLHDHEARHIDGRWKLPALLAYKKKNFDVKT----SE 872

  Fly   301 DMHEDDKFPRTKLLLS------ALQMVDEGYPIPLQGELHTRFQNF-KFTKDLYAPVTNRSPMFG 358
            |:..:|.|...:.|.|      |:|.::|   :|.:.||......| |...||.........|..
 Worm   873 DIISNDLFLAEENLASNGMTSLAVQSLEE---LPKEKELVGLDAEFIKIKTDLLEFDGKTVQMRA 934

  Fly   359 VDCEMCHTEAGCNELTRISIVNENYETVYETLVLPNNRITDYLTQYSGI--------TAEIMEQV 415
            |.      .|.|.:.|...|:.:::..:.:.:     .:.||||::|||        |:|.....
 Worm   935 VG------RASCVDSTGERIIFDDHVKLTDDV-----EVVDYLTKFSGIVKADLCPTTSEKYLTT 988

  Fly   416 TKRLDVVQKEVSELLPPDAILVGQSLNSDLNAMK--MMHPYVIDTSVCFNTSGVRRRKTKLKDLA 478
            .||| :::..|  |:......||.:|::|...:.  :....:|||.......  .:|...|:.|.
 Worm   989 HKRL-LLRMHV--LIQRGVTFVGHALHNDFTVLNVHVAESQIIDTVTLMRLG--TQRMLSLQFLV 1048

  Fly   479 KTFLQEIIQENIDGHDSIEDSRATLKLVKKKLANSIEFGDQIL--TQHKQLQELANASSGDTISN 541
            |..|.|.||  ::.|||:.|:|..|||.:|.|    |..:|.|  ::.:::..:....|.:..|:
 Worm  1049 KEILGETIQ--MEAHDSVVDARYALKLYRKYL----EIKEQGLLGSEMRRIYTILPCPSPNQTSS 1107

  Fly   542 NLFAHVAKRDKRTAIVTVGELQPRLKEVIEKAGEAAPK 579
            .|.....::       |..:..|         .:||||
 Worm  1108 PLVVSTTRK-------TPEDTNP---------ADAAPK 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rexo5	NP_648050.1	REX1_like	357..507	CDD:99848	42/159 (26%)
panl-2	NP_498519.1	WD40	28..324	CDD:475233
		UCH_1	494..>693	CDD:463872	13/54 (24%)
		PAN2_exo	909..1075	CDD:99846	47/183 (26%)