Protein Alignment ndl and PRSS27

DIOPT Version :10

• Sequence 1: NP_523947.2
• Gene: ndl / 38738
• FlyBaseID: FBgn0002926
• Length: 2616
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 92/285 - (32%)
• Similarity: 142/285 - (49%)
• Gaps: 49/285 - (17%)

  Fly  1144 RIVGGSYTSALQWPFVVAIYRNGKFHCGGTIYSDRWIISAAHCVINYGK-YFYEVRAGLLRRSSY 1207
            |:|||..|...:||:.|:|.|||...|||::.:::|:::||||..|..: ..|:|..|..:....
Human    34 RMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQP 98

  Fly  1208 SPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKG---RTTVGDDWIWG 1269
            .|......|..|..:..|:..:...|::|:.|..|:.|..::.|:||||..   .|.:.
Human    99 GPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMN------ 157

  Fly  1270 PVEHTLCTVVGWGAIREKGPSSDP--MRQVIVPI--RKKCT-----------DPEDQASEDICAG 1319
                  |.|.|||:..|:....:|  ::::.|||  ..||.           .|:...::.:|||
Human   158 ------CWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAG 216

  Fly  1320 DPDGGRDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWLEMATTP 1384
            ..:|.:|||:|||||||.|..   ...:..|||:|.|.||||....|||.|||.:.:|:.
Human   217 FEEGKKDACKGDSGGPLVCLV---GQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIH----- 273

  Fly  1385 RLLPKL--QPLQLCPGFICVWGGKR 1407
            |::|||  ||.:|        ||::
Human   274 RIIPKLQFQPARL--------GGQK 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1145..1379	CDD:238113	82/252 (33%)
		LDLa	1399..1430	CDD:238060	2/9 (22%)
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	82/258 (32%)