DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and LOC595077

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	XP_031748571.1	Gene:	LOC595077 / 595077	-ID:	-	Length:	752	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	117/444 - (26%)
Similarity:	183/444 - (41%)	Gaps:	135/444 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1114 CGLPSKSSMLEHSKRVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVAIYRNGKFHCGGTIYSDR 1178
            ||:|              .|||        |||||..:...:||:.:::....:|.|||::.:|.
Frog    26 CGVP--------------VVSD--------RIVGGMNSKKGEWPWQISLNYKNEFICGGSLITDS 68

  Fly  1179 WIISAAHCVINYGKYFYEVRAGLLRRSSYSPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPL 1243
            |:::||||..:....:|.|..|..:.|:...:|..:.|..::.:..:.......|::|:.|..|:
Frog    69 WVMAAAHCFDSLKVSYYTVYLGAYQLSALDNSTVSRGVKKIIKNPNFLYEGSSGDIALMELETPV 133

  Fly  1244 QFNRWVKPICLPDKG-RTTVGDDWIWGPVEHTLCTVVGWGAIREKGPSSDP----MRQVIVPIRK 1303
            .|..::.|:|||.:. :...|          |:|.|.|||..:|..|.|:|    |.:|.:....
Frog   134 TFTPYILPVCLPSQEVQLAAG----------TMCWVTGWGDTQEGIPLSNPKTLQMAEVGIISSS 188

  Fly  1304 KCTDPEDQA----------SED-ICAGDPDGGRDACQGDSGGPLFCRSVSNPDEFYLA-GVVSHG 1356
            .|.|..:.:          .|| :|||..:|..|||||||||||.|    |.:..:|. |:||.|
Frog   189 SCEDMYESSFGYSTGGTFIQEDMVCAGYQEGQIDACQGDSGGPLVC----NVNNVWLQFGIVSWG 249

  Fly  1357 NGCARPQEFGVYTRVTLYLDWLEMATTPRLLPKLQPLQLCPGFICVWGGKRCIAKRQRCDRNVDC 1421
            .|||.|.:.||||:|..|.|||:....
Frog   250 YGCAEPNKPGVYTKVQYYQDWLKTKVP-------------------------------------- 276

  Fly  1422 LGGEDEVGCTYNFLPDMVGGV---RQNISTTTESDYHPVKESEEKSKMREVIPIDDEDLKAEQDE 1483
                        ||....||.   ..:::|||.|      ::|.:|              ....|
Frog   277 ------------FLTFSEGGPSNGSSSVATTTMS------QTEAQS--------------LNSTE 309

  Fly  1484 EDLLKSTTSLGQTETTQGPMDLSFAEQITSTTSDDLSITDETTSTDFTVSDSAT 1537
            .|...||| :.:||.      :|.:.  ::||::..|:...:.||.|.|:|:.|
Frog   310 IDKTNSTT-VFETEA------VSISN--STTTNETFSLIPTSISTVFGVNDTKT 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	81/249 (33%)
		Tryp_SPc	1145..1379	CDD:238113	82/250 (33%)
		LDLa	1399..1430	CDD:238060	0/30 (0%)
		Metaviral_G	1448..1600	CDD:118131	23/90 (26%)
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
LOC595077	XP_031748571.1	Tryp_SPc	35..272	CDD:238113	82/250 (33%)
LOC595077	XP_031748571.1	Tryp_SPc	431..670	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010