DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and zgc:112285

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_001020685.1	Gene:	zgc:112285 / 561476	ZFINID:	ZDB-GENE-050913-132	Length:	316	Species:	Danio rerio

Alignment Length:	303	Identity:	84/303 - (27%)
Similarity:	128/303 - (42%)	Gaps:	73/303 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1111 PMQCGLPS-KSSMLEHSKRVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVAIY---RNGKFH-- 1169
            |..|||.. |.:.:|                   |||.|:......||:.|::.   |..|.:
Zfish    43 PKDCGLAHFKPNTVE-------------------RIVSGNEARPHSWPWQVSLQVRPRGSKHYVH 88

  Fly  1170 -CGGTIYSDRWIISAAHCV------------INYGKYFYEVRAGLLRRSSYSPATQIQPVSHVVV 1221
             ||||:....|:::||||.            |..||:       .|:||  ..|.:..||..:..
Zfish    89 VCGGTLIHKNWVLTAAHCFQKGKAEDASSWRIVLGKH-------QLKRS--ETAERFFPVKRIYR 144

  Fly  1222 HQAYE---RRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPVEHTLCTVVGWGA 1283
            |:.:.   ...:..|::|::....:|.:.:::..|||.|........:.|         |.|||.
Zfish   145 HEHFRYPAHSELDYDIALVKAATDIQPSNFIRYACLPRKQINLNPGHYCW---------VTGWGD 200

  Fly  1284 IR---EKGPSSDPMRQVIVPI--RKKCTDPE---DQASED-ICAG--DPDGGRDACQGDSGGPLF 1337
            .|   |....::.:.|..:||  .|.|...:   |:..:. ||||  |.:|...||||||||||.
Zfish   201 TRGGKENVSLAEALNQARLPIIDYKTCRQKKFWGDRVRDSMICAGFRDTEGTPAACQGDSGGPLL 265

  Fly  1338 CRSVSNPDEFYLAGVVSHGN-GCARPQEFGVYTRVTLYLDWLE 1379
            |:  ...|.:.:.|:||.|. ||....:..|:||...|:.|:|
Zfish   266 CQ--VGRDRWEVHGIVSFGPIGCTVENKPSVFTRTAAYIPWIE 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	76/265 (29%)
		Tryp_SPc	1145..1379	CDD:238113	76/266 (29%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
zgc:112285	NP_001020685.1	Tryp_SPc	58..305	CDD:214473	76/266 (29%)
zgc:112285	NP_001020685.1	Tryp_SPc	59..308	CDD:238113	77/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010