DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and CG4613

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	99/268 - (36%)
Similarity:	144/268 - (53%)	Gaps:	34/268 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1128 RVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVAIYRNGKFHCGGTIYSDRWIISAAHCVINYGK 1192
            ||.|..|.:..:....|||||:.....::|::..|.|.....||||:.:||::::|||||  :|.
  Fly   120 RVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCV--HGM 182

  Fly  1193 YFYEVRAGLL---RRSSYSPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICL 1254
            ....|...||   |.|::...|:....:|  .|..|:..|:.:|::||||..|:.....::|.||
  Fly   183 DMRGVSVRLLQLDRSSTHLGVTRSVAFAH--AHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACL 245

  Fly  1255 PDKGRTTVGDDWIWGPVEHTLCTVVGWGAIREKGPSSDPMRQVIVPIRKKCTDPEDQASE----- 1314
            |        .:|:.. .:.....|.|||..:|.|.:|..:::|:|||   .|:.:.:|:.
  Fly   246 P--------SNWLQN-FDFQKAIVAGWGLSQEGGSTSSVLQEVVVPI---ITNAQCRATSYRSMI 298

  Fly  1315 ---DICAG-DPDGGRDACQGDSGGPLFCRSVSNPDE-FYLAGVVSHGNGCARPQEFGVYTRVTLY 1374
               .:||| ...||||||||||||||..|     |. |.||||||.|.|||:|...||||||:.|
  Fly   299 VDTMMCAGYVKTGGRDACQGDSGGPLIVR-----DRIFRLAGVVSFGYGCAKPDAPGVYTRVSRY 358

  Fly  1375 LDWLEMAT 1382
            |:|:.:.|
  Fly   359 LEWIAVNT 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	93/245 (38%)
		Tryp_SPc	1145..1379	CDD:238113	93/246 (38%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	93/246 (38%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	92/245 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010