Protein Alignment ndl and mas

DIOPT Version :10

• Sequence 1: NP_523947.2
• Gene: ndl / 38738
• FlyBaseID: FBgn0002926
• Length: 2616
• Species: Drosophila melanogaster
• Sequence 2: NP_523919.1
• Gene: mas / 38499
• FlyBaseID: FBgn0011653
• Length: 1047
• Species: Drosophila melanogaster
• Alignment Length: 1212
• Identity: 266/1212 - (21%)
• Similarity: 387/1212 - (31%)
• Gaps: 446/1212 - (36%)

  Fly   346 RNVTTTSASSEPIVDTENTNSDHVPTTENGLVFNITTDGPVETTKSTAQRKLSFDWILDGEENVE 410
            :|.|...|::.|    :.|.:....||:.    ..||.....|||.|.....:      .:...:
  Fly    94 KNATAVRATTTP----KTTTTASTTTTQR----TTTTVATTSTTKRTTTTSTT------PKPKPK 144

  Fly   411 PEVKSTNTTTTTAAT-TTTGATSETIIVTTELPKITFDWIIDGREVVEPQETTTEVTG------- 467
            |:.|...|::||.|| .||...|.|..|.|..||       |..|..:..:...:.||
  Fly   145 PQTKRPATSSTTKATVATTKKPSTTKKVATAKPK-------DKEEATKADDANKDCTGVCVADRI 202

  Fly   468 --------TTERL----------------RKMPFDWIIDGE------------EVVEPQENVTTT 496
                    |::.|                .|:|.|..|..:            |...|.::.:|:
  Fly   203 AEYCEAYLTSDGLCKEGTKCCVSLDEYSNGKLPKDIYIPAKHMSNLKPNQTLSEKSAPAKSSSTS 267

  Fly   497 TIATTVAVSTTEINE--RIHNSTAYPTKPKPVKFDWIIDGGESSGEVSTSSTSQPKLTTREAISN 559
            |.:||...|||...|  ||:||:..|||.|                      ..|..||.||.
  Fly   268 TTSTTTTTSTTTTPEPARINNSSPKPTKHK----------------------KHPTTTTTEAA-- 308

  Fly   560 PESPRSSHPLDNPTSIENMLESFEQHEEQKPILRVLNANESSSETVTDGYERQLWLKKFEDQARP 624
                                   |:.|||              ||..||          |::..|
  Fly   309 -----------------------EEEEEQ--------------ETEEDG----------EEEEPP 326

  Fly   625 NQNELIDTFGTALDAKALDKMGPKINPLNGHTWNAADAQILSLCERVALRMRNKVATMSD----- 684
            ..|:|              |.|            ....|:|..||...  |....|...|
  Fly   327 LSNKL--------------KSG------------QGQGQVLKECEGEC--MNGIFAIFCDDIDSD 363

  Fly   685 ----GETK--EKGETFTASPSVQFTSRAPGGFPVSGETMKASAQFMFNPNFGMPSIPVCFYMTPA 743
                ||..  ..|....|:||    |:||...|......|.:|:         |:.|
  Fly   364 AFCPGEESCCVTGGASEATPS----SKAPPTKPAIKHAPKPAAK---------PARP-------- 407

  Fly   744 NFRMPMWSNTPTFMGMQGAHFGGSSNPGAGIFFVPQQFGPSGNFFGGSGGSGAGGQGANIFS--- 805
                                   :|.|.|         .||..    |||.|.|...:.|.|
  Fly   408 -----------------------ASPPPA---------PPSST----SGGGGGGDFLSQIISFAE 436

  Fly   806 ----KNASPQKPTNGQQQV--------------YC---SYMQNQSGQGAGQSQTSSQQQQGGQSA 849
                ..:.|..|.....||              :|   |.:.:.....|..|......:.|....
  Fly   437 STLNSPSPPPPPPQAPIQVPRCPGFCLLNIMAAFCERPSVLVSTPTTCAKGSVCCDNSRAGAPKP 501

  Fly   850 FSNANFKMRHANQTNTANQQGQIIYASYAGLPQQPIQE-RSRCPEPD-----QFSCFGQQECIPA 908
                  |:.....:.||:...    ..|. ||..|..: |..||...     .|:||...|....
  Fly   502 ------KLPPPTPSPTASPTA----PPYV-LPNTPSPDPREECPGSCIVSLLSFTCFKNAEMTDL 555

  Fly   909 ARWCDNVVDCSDGSDESACTCADRVDEERLCDGYEDC---------PMGEDELGCFGCESLAYSC 964
            .| |..       |.:..|....::.|::......|.         |:|..:  .:..::..||.
  Fly   556 FR-CKR-------SGQICCAPKSKILEKQQFQTRNDTAYYPAPPPPPIGPPQ--AYPPQTPPYSY 610

  Fly   965 YENPQDFAKRNRSTISMCYSRLERCDGFMNCLNGRDEEQCSMLVTDVADHMSHGASASEGYLYHN 1029
            ..||..                          .|...:        :|.|  |...........|
  Fly   611 MNNPPP--------------------------QGPPPQ--------MAPH--HPNPYQPPPPAPN 639

  Fly  1030 YRGDWHPVCNNGEKWAALACQMDENSRMDHSASLNVSFQTLTLPGPF--------IEPSLHAG-- 1084
            | .|::||...|     |..|.........:.:     .|.|.|.|.        ::.:|..|
  Fly   640 Y-ADYYPVSGPG-----LPPQPQPPMTTPPTTT-----TTTTTPRPHVYSKYVCGVKGTLRTGRS 693

  Fly  1085 -----VHFAQACHG------------------RNSHDSLVDHVAYVKCPPMQ-----CGLPSKSS 1121
                 |.:|:|.:|                  ..|::.||...|.|   |:|     .|...:||
  Fly   694 QALSFVSYARAKYGVQRTARQMTSAAGYSPNFNKSNERLVLGSAIV---PIQIHNDKLGDLVESS 755

  Fly  1122 MLEHSKRVR-----RAVSDSKEIV--------------------GDGRIVGGSYTSALQWPFVVA 1161
            .|: |.::|     :|.:|..::|                    ...|:|||......:|.:.||
  Fly   756 SLQ-SNQLRSYHNHQAQADQPDLVYPEYYQQRSLYGLQSNFSGRRRARVVGGEDGENGEWCWQVA 819

  Fly  1162 IYRN-GKFHCGGTIYSDRWIISAAHCVINY---GKYFYEVRAG--LLRRSSYSPATQIQPVSHVV 1220
            :..: .::.||..:...:|:::|||||.|.   |...| ||.|  .|.|...||..|...|:...
  Fly   820 LINSLNQYLCGAALIGTQWVLTAAHCVTNIVRSGDAIY-VRVGDYDLTRKYGSPGAQTLRVATTY 883

  Fly  1221 VHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPVEHTL---CTVVGWG 1282
            :|..:..:::.||::||:|....:....|..:|||.:|            |.|..   |||.|:|
  Fly   884 IHHNHNSQTLDNDIALLKLHGQAELRDGVCLVCLPARG------------VSHAAGKRCTVTGYG 936

  Fly  1283 AIREKGPSSDPMRQVIVPI--RKKCTDPEDQASEDI--------CAGDPDGGRDACQGDSGGPLF 1337
            .:.|.||....:|:..:||  ..:|....:..:|.|        |||..: |.||||||.||||.
  Fly   937 YMGEAGPIPLRVREAEIPIVSDTECIRKVNAVTEKIFILPASSFCAGGEE-GHDACQGDGGGPLV 1000

  Fly  1338 CRSVSNPDEFY-LAGVVSHGNGCARPQEFGVYTRVTLYLDWL 1378
            |:.    |.|| |||:||.|.||.|....|||.:.:.::.|:
  Fly  1001 CQD----DGFYELAGLVSWGFGCGRQDVPGVYVKTSSFIGWI 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060	9/40 (23%)
		Tryp_SPc	1145..1379	CDD:238113	84/254 (33%)
		LDLa	1399..1430	CDD:238060
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
mas	NP_523919.1	CLIP_SPH_mas	55..87	CDD:465746
		CLIP_SPH_mas	192..224	CDD:465746	4/31 (13%)
		CLIP_SPH_mas	343..374	CDD:465746	7/32 (22%)
		CLIP_SPH_mas	457..492	CDD:465746	4/34 (12%)
		CLIP_SPH_mas	532..567	CDD:465746	9/42 (21%)
		Tryp_SPc	803..1041	CDD:238113	84/254 (33%)