DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ndl and CG4927

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_001033953.1	Gene:	CG4927 / 36852	FlyBaseID:	FBgn0034139	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	100/357 - (28%)
Similarity:	148/357 - (41%)	Gaps:	90/357 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1075 PFIEPSLHAGVHFAQACHGRNSHDSLVDHVAYVKCPPMQCGLPS----KSSMLEHSKRVRRAVSD 1135
            |.|..:||...:|.:.|...|          ::.|    |.||:    :|.....:..:||...:
  Fly    38 PSIFFNLHLIRNFVKYCDKSN----------HIVC----CLLPNNMQPQSQQFSANIGLRRFEKE 88

  Fly  1136 SK---EIVGDGR----IVGGSYTSALQWPFVVAIYRNGK------FHCGGTIYSDRWIISAAHCV 1187
            .:   ||....|    ||||:..:..::||:..:.:.||      :.||..|...:::::||||:
  Fly    89 CRRFNEIRTSCRTTPFIVGGAKAAGREFPFMALLGQRGKNSSQIDWDCGAIIIHPKFVLTAAHCL 153

  Fly  1188 -----------INYGKYFYEVRAGLLRRSSYSPATQIQP--VSHVVVHQAY----ERRSMRNDLS 1235
                       .||....|.||.|.|..:|.:...|.|.  |.:.|||.||    :..|.:||::
  Fly   154 ETSETKEQRLDPNYDGPKYVVRLGELDYNSTTDDAQPQDFRVLNYVVHPAYGEDDDTGSRKNDIA 218

  Fly  1236 LLRLLNPLQFNRWVKPICLP-DKGRTTVGDDWIWGPVEHTLCTVVGWGAIREKGPSSDPMRQVIV 1299
            ::.|.....|:.:|.|.||| |.|.            |.......||||..|.|.:|..:.:|.:
  Fly   219 VVELEMEATFSEYVAPACLPLDGGN------------EQLQVAAAGWGATSESGHASSHLLKVSL 271

  Fly  1300 PIRKKCTDPEDQAS------------EDICAGDPDGGRDACQGDSGGPLFCRSVSNPDEFY---- 1348
                   |..|.|.            ..:|||......|.|.||||||:|   |.:|  .|
  Fly   272 -------DRYDVAECSQRLEHKIDVRTQLCAGSRSTSADTCYGDSGGPVF---VQHP--IYSCLK 324

  Fly  1349 -LAGVVSHGNGCARPQEFGVYTRVTLYLDWLE 1379
             :.|:.|:|..|.......|||:|.||.||:|
  Fly   325 QVIGITSYGLVCGVQGLPSVYTKVHLYTDWIE 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	81/277 (29%)
		Tryp_SPc	1145..1379	CDD:238113	82/274 (30%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	83/276 (30%)
CG4927	NP_001033953.1	Tryp_SPc	105..355	CDD:214473	81/273 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100