DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and CG3355

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	94/292 - (32%)
Similarity:	148/292 - (50%)	Gaps:	61/292 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1108 KCPPMQ---CGLPSKSSMLEHSKRVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVAIYRN---G 1166
            :|...|   ||.|:.:                       |||||....:.::|:...:.:.   .
  Fly    59 QCTAKQNCFCGTPNVN-----------------------RIVGGQQVRSNKYPWTAQLVKGRHYP 100

  Fly  1167 KFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRRSSYSPATQIQPVSHVVVHQAYERRSMR 1231
            :..|||::.:||::::||||| :..:....:|...:.|||..|.. ::.|....||..|:...:.
  Fly   101 RLFCGGSLINDRYVLTAAHCV-HGNRDQITIRLLQIDRSSRDPGI-VRKVVQTTVHPNYDPNRIV 163

  Fly  1232 NDLSLLRLLNPLQFNRWVKPICLPD-----KGRTTVGDDWIWGPVEHTLCTVVGWGAIREKGPSS 1291
            ||::||:|.:|:.....::|:|||:     .|:|.|               |.|||.|:|.|.:|
  Fly   164 NDVALLKLESPVPLTGNMRPVCLPEANHNFDGKTAV---------------VAGWGLIKEGGVTS 213

  Fly  1292 DPMRQVIVPI--RKKC--TDPEDQASE-DICAG-DPDGGRDACQGDSGGPLFCRSVSNPDEFYLA 1350
            :.:::|.||:  ..:|  |..:|:.:| .:||| ...||:|||||||||||    :.|...:.||
  Fly   214 NYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQQGGKDACQGDSGGPL----IVNEGRYKLA 274

  Fly  1351 GVVSHGNGCARPQEFGVYTRVTLYLDWLEMAT 1382
            ||||.|.|||:....|||.||:.:|||:...|
  Fly   275 GVVSFGYGCAQKNAPGVYARVSKFLDWIRKNT 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	86/246 (35%)
		Tryp_SPc	1145..1379	CDD:238113	87/247 (35%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	87/247 (35%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	87/249 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010