DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and CG30375

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_724665.1	Gene:	CG30375 / 246575	FlyBaseID:	FBgn0050375	Length:	398	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	100/454 - (22%)
Similarity:	180/454 - (39%)	Gaps:	130/454 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   979 ISMCYSRL----ERCDGFMNCLNGR--------------DEEQCSMLVTDVADHMSH-------- 1017
            :|:.|..|    ::|..|.:.:..|              ....|...:...::|:.:
  Fly    10 LSLLYISLSCAQQQCTRFFDLIPNRTINITSFNYPGAIPSGSNCRFRLKAPSNHVIYLSCRFELF 74

  Fly  1018 -GASASEGYLYHNYRGDWHPVCNNGEKWAALACQMDENSRMDHSASLNVSFQTLTLPGPFIEPSL 1081
             ....|| :|:.:..||..  ..:||::    |:|.:.:|:.       :|||:
  Fly    75 PDTCGSE-FLFISRDGDLQ--FRDGERY----CRMGQVNRIS-------NFQTM----------- 114

  Fly  1082 HAGVHFAQACHGRNSHDSLVDHVAYVKCPPMQCG--LPSKSSMLEHSKRVRRAVSDSKEIVGDGR 1144
             |..:::.:  .:....|.::..|..:..|..||  .|:                         |
  Fly   115 -AFAYYSSS--PQTQQRSRLNCQAVARPAPCDCGWSFPN-------------------------R 151

  Fly  1145 IVGGSYTSALQWPFVVA---IYRNGKFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLL---- 1202
            |..|......::|.:|.   :..|....|||:|.|:|:|::||||...     ..|.:.||
  Fly   152 IANGVEAGKHEFPSMVGLRDLSSNLPIFCGGSIVSERYIMTAAHCTAR-----QPVASRLLALVG 211

  Fly  1203 -------RRSSYSPATQIQPVSHVVVHQAYERRSMR--NDLSLLRLLNPLQFNRWVKPICLPDKG 1258
                   ..|.|:...:||   :::.|..|...:..  ||::||:...|::::|.|.|||||.:
  Fly   212 EHDLSTGAESIYAAQYRIQ---NIINHPGYMETASGNINDIALLQTATPIEWSRGVAPICLPIR- 272

  Fly  1259 RTTVGDDWIWGPVEHTL----CTVVGWGAIREKGPSSDPMRQ--VIVPIRKKCTDPEDQA--SED 1315
                       ..|::.    ..::|||.:......|:.:::  ::......|....:.:  ...
  Fly   273 -----------QAENSFNYQNVDIMGWGTLGFAASKSNTLQKATLLTMDNAVCRSRFNSSITPSH 326

  Fly  1316 ICAGDPDG-GRDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWL 1378
            :|..|..| |:|:||.|||||:..|   ..:..:..||:|:|..|.:|...||.||||.:|:||
  Fly   327 LCTYDAGGRGQDSCQYDSGGPVILR---QRERMFQLGVISYGRACGQPFGIGVNTRVTSHLNWL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	70/257 (27%)
		Tryp_SPc	1145..1379	CDD:238113	71/259 (27%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
CG30375	NP_724665.1	CUB	38..>100	CDD:294042	9/68 (13%)
		Tryp_SPc	151..386	CDD:214473	70/257 (27%)
		Tryp_SPc	152..387	CDD:238113	69/257 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100