DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and zgc:163079

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	NP_001077051.2	Gene:	zgc:163079 / 100006550	ZFINID:	ZDB-GENE-030131-7428	Length:	313	Species:	Danio rerio

Alignment Length:	271	Identity:	70/271 - (25%)
Similarity:	120/271 - (44%)	Gaps:	41/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1144 RIVGGSYTSALQWPFVVAIYRNG--KFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRRSS 1206
            :|:||...:...||:..:|....  :|:|||::.:..|:::.|............|..|...::.
Zfish    35 KIIGGLNATQGSWPWQASINLKATEEFYCGGSLINKGWVLTTAKVFALMPASDIVVYLGRQTQNG 99

  Fly  1207 YSPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPV 1271
            .:|....:.|:.::.|..|  .|:.::|:||:|.:|:.|:.::||:||...|...|.....|
Zfish   100 SNPYEISRTVTKIIKHPNY--NSLDSNLALLKLSSPVTFSDYIKPVCLAAAGSVFVDGTASW--- 159

  Fly  1272 EHTLCTVVGWGAIREKGPSS-------DPMRQVIVPI--RKKCTDPEDQ--ASEDICAGD-PDGG 1324
                  |.|||.:..  |::       |.:::|..||  ..:|......  .::.:|||. .:.|
Zfish   160 ------VTGWGYLNR--PATVEEIMLPDVLQEVEAPIVNNFECNAAYGGIITNKLLCAGYLNEDG 216

  Fly  1325 RDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWLEMATTPRLLPK 1389
            :..|.||.||||.   :.....:..:|||..|. |..|....:|.||:.|.||:...|...|
Zfish   217 KAPCAGDVGGPLV---IKQGAIWIQSGVVVSGY-CGLPGYPTIYVRVSEYEDWISYYTNSSL--- 274

  Fly  1390 LQPLQLCPGFI 1400
                   |||:
Zfish   275 -------PGFV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	63/246 (26%)
		Tryp_SPc	1145..1379	CDD:238113	65/247 (26%)
		LDLa	1399..1430	CDD:238060	1/2 (50%)
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
zgc:163079	NP_001077051.2	Tryp_SPc	35..266	CDD:214473	64/247 (26%)
zgc:163079	NP_001077051.2	Tryp_SPc	36..267	CDD:238113	65/247 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010