DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ndl and si:dkey-16l2.17

DIOPT Version :9

Sequence 1:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster
Sequence 2:	XP_001341498.1	Gene:	si:dkey-16l2.17 / 100001520	ZFINID:	ZDB-GENE-141212-262	Length:	305	Species:	Danio rerio

Alignment Length:	264	Identity:	90/264 - (34%)
Similarity:	132/264 - (50%)	Gaps:	42/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1144 RIVGGSYTSALQWPFVVAIYRNGKFH-CGGTIYSDRWIISAAHCVINYGKY-FYEVRAGLLRRSS 1206
            |||||...|...||:.|.|......| |||:|.:..|::|||||..|..:. .|.:..|....:.
Zfish    31 RIVGGVEASPGSWPWQVDIQMGSNGHVCGGSIIAKNWVLSAAHCFPNPSEVSAYTLYMGRHLLNG 95

  Fly  1207 YSPATQIQPVSHVVVHQAYERRSMRNDLSLLRLLNPLQFNRWVKPICLP------DKGRTTVGDD 1265
            |:...::..|..||:.:.|.......|::|::|..|:.:...::|:|||      :.|
Zfish    96 YNQFEKVSYVQRVVIPEGYTDPQGGRDVALVQLRAPVSWTDRIQPVCLPFADFQFNSG------- 153

  Fly  1266 WIWGPVEHTLCTVVGWGAIREKGPS---SDPMRQVIVPI--RKKC----------TDPEDQASED 1315
                    |||.|.|||. :::|.|   :..:|:|.|||  :..|          :...|..|:.
Zfish   154 --------TLCYVTGWGH-KQEGVSLTGAAALREVEVPIIDQSSCQFMYQILSSDSSTVDILSDM 209

  Fly  1316 ICAGDPDGGRDACQGDSGGPLFCRSVSNPDEFYLAGVVSHGNGCARPQEFGVYTRVTLYLDWLEM 1380
            ||||..:||:|:|||||||||.| .|.| ..:..|||||.|.|||:....|:|:||:.: :.|..
Zfish   210 ICAGYKEGGKDSCQGDSGGPLVC-PVGN-GTWIQAGVVSFGLGCAQKNRPGIYSRVSSF-EKLIR 271

  Fly  1381 ATTP 1384
            .|.|
Zfish   272 TTVP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	87/255 (34%)
		Tryp_SPc	1145..1379	CDD:238113	86/256 (34%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
si:dkey-16l2.17	XP_001341498.1	Tryp_SPc	32..273	CDD:238113	87/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_112858
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910