Protein Alignment sfl and HS3ST3B1

DIOPT Version :10

• Sequence 1: NP_001401031.1
• Gene: sfl / 38736
• FlyBaseID: FBgn0020251
• Length: 1129
• Species: Drosophila melanogaster
• Sequence 2: NP_006032.1
• Gene: HS3ST3B1 / 9953
• HGNCID: 5198
• Length: 390
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 85/311 - (27%)
• Similarity: 137/311 - (44%)
• Gaps: 44/311 - (14%)

  Fly   713 ASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVRHKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTF 777
            |::|..|..|:     |:...|:           ..:........||:.::||.:|.||.||..|
Human   108 AASPEEQSPEV-----PDSPSPI-----------SSFFSGSGSKQLPQAIIIGVKKGGTRALLEF 156

  Fly   778 LSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKS 842
            |.:|..:.:..|.|..|:       .:|.:||.||.|.            ||..|.. :...||:
Human   157 LRVHPDVRAVGAEPHFFD-------RSYDKGLAWYRDL------------MPRTLDG-QITMEKT 201

  Fly   843 ATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPR 907
            .:||.....|.|..|:....|::.::..|..||.|.|....|....|..    ::.:|..:.. .
Human   202 PSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPT----FESLTFKNRT-A 261

  Fly   908 ALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNH 972
            .|.|.....:..|.||:||||||.::|.:|:..:.||:|..:|...:..:|.||.::.::. ..|
Human   262 GLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIIT-DKH 325

  Fly   973 LRYDVKKGFYC--QAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHN 1021
            ..::..|||.|  :|....|..||||:|||.:|.:|....:.|:.:|...|
Human   326 FYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFN 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001401031.1	HSNSD	240..669	CDD:463450
		Sulfotransfer_1	758..1017	CDD:425820	77/260 (30%)
HS3ST3B1	NP_006032.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..133		6/40 (15%)
		Sulfotransfer_1	137..374	CDD:425820	78/262 (30%)