DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sfl and hs3st4

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001074058.2	Gene:	hs3st4 / 563570	ZFINID:	ZDB-GENE-070202-8	Length:	422	Species:	Danio rerio

Alignment Length:	304	Identity:	91/304 - (29%)
Similarity:	141/304 - (46%)	Gaps:	54/304 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   754 NCDS------LPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWY 812
            ||.|      ||:.::||.:|.||.||...|.:|..:.:....|..|:       .||.:|||||
Zfish   147 NCTSDYGEKKLPQAIIIGVKKGGTRALLEALRVHPDVRAVGNEPHFFD-------RNYEKGLDWY 204

  Fly   813 MDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYS 877
            .:..||           |..|  :...||:.:||...:.|||.|.:....|::.::.:|..||.|
Zfish   205 RELMPS-----------TLEG--QITMEKTPSYFVTNSAPKRIHTMARDIKLIIVVRNPVTRAIS 256

  Fly   878 WYQHQRSHG------DVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQ 936
            .|....|..      :|:|.......:|.||.||           |..|.||.|||.|:.|:|..
Zfish   257 DYTQTLSKRPEIPTFEVLAFKNRTLGLIDASWSA-----------LRIGIYALHLESWMQYFPLS 310

  Fly   937 QLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRN--KCLGKSKG 999
            |:|.:.||:|.::|...|.::|.||.::.::. ..|..::..|||.|....|..:  :|||||||
Zfish   311 QMHFVSGERLIVDPAGEMAKVQDFLGLKRIVT-DKHFYFNKTKGFPCLKKPEDSSTPRCLGKSKG 374

  Fly  1000 RQYPAMDERSAKLLQRYYLNHNTALVKL--------LKKLGSRP 1035
            |.:|.:|....:.|.::|...|....::        |::.|:.|
Zfish   375 RTHPKIDPDVIRRLHKFYKPFNMMFYQMTGQNFQWELEEDGNSP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	83/266 (31%)
hs3st4	NP_001074058.2	Sulfotransfer_1	157..394	CDD:279075	84/268 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592772
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740