DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sfl and hs3st1l2

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001035015.1	Gene:	hs3st1l2 / 562344	ZFINID:	ZDB-GENE-070202-3	Length:	303	Species:	Danio rerio

Alignment Length:	280	Identity:	86/280 - (30%)
Similarity:	132/280 - (47%)	Gaps:	50/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   750 SKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFN-GNNYYRGLDWYM 813
            |.......||..::||.:|.||.||...|::|..:  .:|.    .|:.:|| ..|:.:|||||
Zfish    42 SNASTLQRLPGAIIIGVRKGGTRALLEMLNLHPDV--EVAK----TEIHYFNLDENFRKGLDWY- 99

  Fly   814 DFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSW 878
                ...:|.|   :|.||     ..||:..||.....|:|..|:.|..|::.|:..||:|..|.
Zfish   100 ----RSQMPIT---LPGQL-----TVEKTPGYFTAPPAPRRIWAMNPAVKLLLIIRDPAERLVSD 152

  Fly   879 YQ---HQRSHGDVIANNYSFYQVITASDSAPRALKDL---------RNRCLNPGKYAQHLEHWLA 931
            |.   |.|     |..|..:           ::|::|         :.:.|....|.|||..||.
Zfish   153 YTQVLHNR-----IQQNKPY-----------QSLEELLLSQGHINPKYKALQRSFYYQHLARWLE 201

  Fly   932 YYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGK 996
            .:|.:|:||:|||.|..||...:.:.:.||::.|.:...| ..::|.|||||. :|...:|||.:
Zfish   202 LFPREQIHIVDGEALIRNPFPELQKAETFLELPPQIKPDN-FYFNVTKGFYCM-LSAGHDKCLDE 264

  Fly   997 SKGRQYPAMDERSAKLLQRY 1016
            ||||.:..:...:.:.|.||
Zfish   265 SKGRPHAPLSNEAFQKLCRY 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	85/272 (31%)
hs3st1l2	NP_001035015.1	Sulfotransfer_1	54..285	CDD:279075	83/268 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592774
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740