DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sfl and hs3st3b1b

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001074037.1	Gene:	hs3st3b1b / 558084	ZFINID:	ZDB-GENE-070202-5	Length:	396	Species:	Danio rerio

Alignment Length:	323	Identity:	93/323 - (28%)
Similarity:	144/323 - (44%)	Gaps:	38/323 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 WTNLKL-ASAPPVQLAEMYFRLHPEEVDPV--WGNPCDDVRHKKIWSKTKN---CDSLPKFLVIG 765
            ||:::. ...|.|:.|...|.....:.|..  |    ||.|.....|...|   ...||:.::||
Zfish    90 WTDVESDYDEPAVRRALRDFSKDEGDADRAEEW----DDGRRVSALSTFSNGSGSKKLPQAIIIG 150

  Fly   766 PQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPT 830
            .:|.||.||..||.:|..|.:..|.|..|:       .||..|||||.|..|.           |
Zfish   151 VKKGGTRALLEFLRVHPDIRAVGAEPHFFD-------RNYENGLDWYRDLMPK-----------T 197

  Fly   831 QLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSF 895
            ..|  :...||:.:||.....|.|.:|:....|::.::..|..||.|.|....|....|..
Zfish   198 LEG--QITMEKTPSYFVTREAPSRIYAMSRDTKLIVVVRDPVTRAISDYTQTLSKKPDIPT---- 256

  Fly   896 YQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRF 960
            ::.:|..:.. ..|.|.....:..|.||:||::||.::|..|:..:.||:|..:|...:..:|.|
Zfish   257 FESLTFKNRT-TGLIDTSWSAIQIGIYAKHLDNWLQFFPMSQILFVSGERLISDPAGELGRVQDF 320

  Fly   961 LKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNK--CLGKSKGRQYPAMDERSAKLLQRYYLNHN 1021
            |.::.::. ..|..::..|||.|...:|..:|  ||||:|||.:|.:|....:.|:.:|...|
Zfish   321 LGLKRIIT-DKHFYFNQTKGFPCLKKAEGSSKPHCLGKTKGRTHPNIDPEVVQRLRDFYRPFN 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	78/260 (30%)
hs3st3b1b	NP_001074037.1	Sulfotransfer_1	143..384	CDD:279075	80/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810