DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sfl and Hs3st3a1

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001165538.1	Gene:	Hs3st3a1 / 363618	RGDID:	1561262	Length:	393	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	80/266 - (30%)
Similarity:	124/266 - (46%)	Gaps:	28/266 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   758 LPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLP 822
            ||:.::||.:|.||.||..||.:|..:.:..|.|..|:       .:|::||.||.|.
  Rat   139 LPQAIIIGVKKGGTRALLEFLRVHPDVRAMGAEPHFFD-------RSYHKGLAWYRDL------- 189

  Fly   823 NTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGD 887
                 ||..| ..:...||:.:||.....|.|..|:....|::.::..|..||.|.|....|...
  Rat   190 -----MPRTL-EGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 248

  Fly   888 VIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPID 952
            .|.   ||..:...:.||  .|.|.....:..|.||:|||.||.::|..|:..:.||:|..:|..
  Rat   249 DIP---SFESLTFRNRSA--GLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAG 308

  Fly   953 VMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNK--CLGKSKGRQYPAMDERSAKLLQR 1015
            .:..:|.||.::.::. ..|..::..|||.|...:|...|  ||||:|||.:|.:.....:.|:.
  Rat   309 ELRRVQDFLGLKRIIT-DKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRD 372

  Fly  1016 YYLNHN 1021
            :|...|
  Rat   373 FYRPFN 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	78/260 (30%)
Hs3st3a1	NP_001165538.1	Sulfotransfer_1	139..376	CDD:279075	79/262 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740