DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sfl and Hs3st5

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001099862.1	Gene:	Hs3st5 / 294449	RGDID:	1306379	Length:	346	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	77/261 - (29%)
Similarity:	129/261 - (49%)	Gaps:	23/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   758 LPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFF-NGNNYYRGLDWYMDFFPSESL 821
            |||.::||.:|.||.||...|::|.::.      :..:|:.|| |..||.:|::||....|..
  Rat    90 LPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYAKGIEWYRKKMPFS-- 146

  Fly   822 PNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHG 886
                  .|.|:     ..|||..||..|.||:|.:.:....|::.|:..|..||.|.|.......
  Rat   147 ------YPQQI-----TIEKSPAYFITEEVPERIYKMNSSIKLLMIVREPTTRAISDYTQVLEGK 200

  Fly   887 DVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPI 951
            :  ..|.::|:....:........:.:.:.:....|.:|||.||.|:|.:|.||:||::|...|:
  Rat   201 E--RKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPL 263

  Fly   952 DVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRY 1016
            ..:..:::||.:.|.:...| |.::..:||||...:...||||..||||.:|.:|......|:::
  Rat   264 PELQLVEKFLNLPPRISQYN-LYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKF 327

  Fly  1017 Y 1017
            :
  Rat   328 F 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	77/259 (30%)
Hs3st5	NP_001099862.1	Sulfotransfer_1	90..330	CDD:279075	77/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810