DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sfl and hs3st3l

DIOPT Version :9

Sequence 1:	NP_001163354.1	Gene:	sfl / 38736	FlyBaseID:	FBgn0020251	Length:	1048	Species:	Drosophila melanogaster
Sequence 2:	NP_001074909.1	Gene:	hs3st3l / 100008592	ZFINID:	ZDB-GENE-070202-6	Length:	334	Species:	Danio rerio

Alignment Length:	284	Identity:	87/284 - (30%)
Similarity:	132/284 - (46%)	Gaps:	52/284 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   758 LPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLP 822
            ||..|:||.:|.||.||..||.:|..|.:..|.|..|:       .:|.|||.||
Zfish    81 LPHALIIGVKKGGTRALLEFLRLHPDIRALGAEPHFFD-------RHYSRGLGWY---------- 128

  Fly   823 NTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGD 887
              .|.||..|.. :.:.||:..||.....|.|.||:..:.|::.::.:|..||.|.|.
Zfish   129 --RSMMPKALNG-QIVMEKTPRYFVTPETPGRIHAMSKNIKLIVVVRNPITRAISDYT------- 183

  Fly   888 VIANNYSFYQVITASDSAPRALKDL--RNRC----------LNPGKYAQHLEHWLAYYPAQQLHI 940
                     |:|:.:...| :.:.|  :||.          |..|.||:|||.||||:|..|:|.
Zfish   184 ---------QIISKTPDIP-SFESLTFKNRSTGQIDALWSPLYIGLYAKHLERWLAYFPLSQIHF 238

  Fly   941 IDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNK--CLGKSKGRQYP 1003
            :.||:|..:|...:..:|.||.::.::. ..|..::..|||.|....|..:|  ||||:|||.:.
Zfish   239 VHGERLISDPAGELGRVQDFLGLERIIT-DKHFYFNKTKGFPCLKKPEGSSKPHCLGKTKGRTHA 302

  Fly  1004 AMDERSAKLLQRYYLNHNTALVKL 1027
            .:|....:.|:.:|..||....::
Zfish   303 RIDPDVIQKLREFYQPHNLRFYRM 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sfl	NP_001163354.1	HSNSD	179..669	CDD:288882
sfl	NP_001163354.1	Sulfotransfer_1	758..1017	CDD:279075	84/272 (31%)
hs3st3l	NP_001074909.1	Sulfotransfer_1	81..319	CDD:279075	85/275 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810