Protein Alignment Bulli and rmc1

DIOPT Version :10

• Sequence 1: NP_648047.2
• Gene: Bulli / 38734
• FlyBaseID: FBgn0035703
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001349475.1
• Gene: rmc1 / 494078
• ZFINID: ZDB-GENE-041212-46
• Length: 654
• Species: Danio rerio
• Alignment Length: 650
• Identity: 241/650 - (37%)
• Similarity: 391/650 - (60%)
• Gaps: 31/650 - (4%)

  Fly     5 NGIHYIELTPNPIRFDAVSQLTNVFFDDSNKQIFAVRSGGATGVVVKGPGSPDDVVISFCMSDRG 69
            |..:|:||:.||::|:..|.:.|||||::|||:||||||||||||||||  .|...::|.|.|:
Zfish     2 NDEYYLELSENPVQFENASSVNNVFFDEANKQVFAVRSGGATGVVVKGP--DDKSSVAFRMDDK- 63

  Fly    70 GAIRSIKFSPDNQILAVQRKENSVEFICFQGDQPLLQDIITHQVKT---LIHGFVWVHNREVALI 131
            |.::.||||..|:||||||...||:||.|..|.|.|:  .:|:.||   .|.||.|.:..|:..:
Zfish    64 GEVKCIKFSLGNKILAVQRTTKSVDFINFIPDYPHLE--FSHECKTKNASILGFCWTNWNEIVFV 126

  Fly   132 SNTGVEVYTVVPEKRQVRSVKSLSIGIKWFAWCCDANVALLCTS-EGNSLIPVLVKQKVITKLPK 195
            ::.|:|.|.|:|:||.::.:||.||.:.|:.:|.:..|.||.|: :||.|.|...|...::|:.|
Zfish   127 TDQGIEFYQVLPDKRTLKLLKSQSINVNWYIYCPETAVLLLSTTVQGNVLQPFAFKTATMSKMSK 191

  Fly   196 VDLGNPS------RDVQESKVTLGQVYGVLAVLILQSNS-TTGLMEVEVHLLNGP--GLAPRKCH 251
            .::..|:      ..:.|..:.:..:|..|.|:.|:.:| ||.....||.|.:.|  |.. ::.:
Zfish   192 FEIELPAVPKPAKLSLSERDIAVATIYDQLYVMYLKHHSRTTNSPGAEVVLYHLPREGTC-KRTN 255

  Fly   252 VLRLSLLGRFAINTVDNLIVVHHQASGTSLLFDISLPGEVINEITYHTPITPGRSIKPFGLKL-- 314
            ||||:..|:||||.||||:|||||::.|||::||.| .|:...:..|.|:.|.|||.||.:.|
Zfish   256 VLRLNTTGKFAINVVDNLVVVHHQSTQTSLIYDIKL-RELDGNVNVHQPVLPARSINPFKIPLTG 319

  Fly   315 PSLSPDGQILQCELYSTHWVLFQPNIVIDAKLGCMWFLNLCIEPLCQLISDRIRLTEFLLQRSNG 379
            |:.:|....|.|||||:.|.:|||:|:|.|..|.:|:|.:.::|...|:.|:.:|.:|||:|.:.
Zfish   320 PAAAPSQAPLPCELYSSSWSVFQPDIIISASEGFLWYLQVKLQPTLNLLQDKGKLMDFLLRRRDC 384

  Fly   380 KQMLLKVIGQLVDDQYKGTLLPVLETIFSRINKIYASWVQLELQNQTAQPSN-VKTTTLKQSTPP 443
            |.::|.|..|::....||. |.|:.|:|.::|::|..::..|.....|..|. .:::..|:....
Zfish   385 KMVILSVCSQMLIGGDKGN-LSVVATVFDKLNQVYKEYLDAEQAYTAAMESGPSRSSAYKRPVRT 448

  Fly   444 IVLIEQLDM----VQIF--QRIARRPYTESILMLYLQSLNKFNIAAQEELSKMIISELISNRSFD 502
            ..:|:|.||    :..|  ::..:..:..:::|.|::|||:|.|..|..|.:::|..|:.:..|.
Zfish   449 QAVIDQSDMYTHVLSDFTEKKEVKHKFIIAVVMEYIRSLNQFQIPVQHYLYELVIKTLVQHNLFY 513

  Fly   503 TLRRLVSYSMLLESKSVACFLLSHSNVDTAISQVAIDMLGRIE-AHEIIIEVMLGQGKVIDALRL 566
            .|.:.:.|.:|.:||.:||.|||..:......|:::|||.|:. |::.|:||:|.:.:|:.|||.
Zfish   514 MLHQFLQYHVLTDSKPLACLLLSLESTYPPAYQLSLDMLKRLSTANDEIVEVLLSKQQVLGALRF 578

  Fly   567 AKNSMGLEKVPARKFLEAAHKTKDDLIFHSVYRFFQMRNLKLYETLSFPKAEQCTEFIQHYNNTF 631
            .::..|.:...|||||:||.:|.|.::|::::|||:.||::|.....|...|.|.|.:.::...|
Zfish   579 IRSVGGHDNASARKFLDAARQTNDTMLFYTIFRFFETRNMRLRGNPGFNPGEHCEEHVSYFKQVF 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bulli	NP_648047.2	Mic1	461..617	CDD:429257	54/156 (35%)
rmc1	NP_001349475.1	Mic1	472..629	CDD:429257	54/156 (35%)