Protein Alignment Bulli and Rmc1

DIOPT Version :10

• Sequence 1: NP_648047.2
• Gene: Bulli / 38734
• FlyBaseID: FBgn0035703
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001009638.1
• Gene: Rmc1 / 291784
• RGDID: 1311805
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 242/659 - (36%)
• Similarity: 386/659 - (58%)
• Gaps: 53/659 - (8%)

  Fly     8 HYIELTPNPIRFDAVSQLTNVFFDDSNKQIFAVRSGGATGVVVKGPGSPDDVVISFCMSDRGGAI 72
            :|:||...|::|:..:.:..||||::|||:||||||||||||||||  .|...|||.|.|| |.:
  Rat     6 YYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGP--DDRNPISFRMDDR-GEV 67

  Fly    73 RSIKFSPDNQILAVQRKENSVEFICFQGDQPLLQDIITHQVKTL---IHGFVWVHNREVALISNT 134
            :.||||.:|:||||||...:|:|..|..|...|:  .|.:.||.   |.||.|..:.|:..|::.
  Rat    68 KCIKFSLENKILAVQRTSKAVDFCNFIPDNSQLE--YTQECKTKNANILGFCWTSSTEIVFITDQ 130

  Fly   135 GVEVYTVVPEKRQVRSVKSLSIGIKWFAWCCDANVALLCTSE-GNSLIPVLVKQKVITKLPKVDL 198
            |:|.|.|:||||.::.:||.:|.:.|..:|.:::|.||.|:. .|.|.|...|...::||||.::
  Rat   131 GIEFYQVLPEKRSLKLLKSHNINVNWHMYCPESSVILLSTTVLENVLQPFYFKAGTMSKLPKFEI 195

  Fly   199 GNPSR------DVQESKVTLGQVYGVLAVLILQ-----SNSTTGLMEVEVHLLNGPGLAPRKCHV 252
            ..|:.      .:.|..:.:..:||.|.||.|:     ||||..  ||.::.|...| |.:|.|:
  Rat   196 ELPAAPKSTKLSLSERDIAMATIYGQLYVLFLRHHSRTSNSTGA--EVVLYHLPREG-ACKKMHI 257

  Fly   253 LRLSLLGRFAINTVDNLIVVHHQASGTSLLFDISLPGEVINEITYHTPITPGRSIKPFGLKL--P 315
            |:|:..|:||:|.||||:|||||.:.||::|||.|.||....:|:|.|:.|.|||:|:.:.|  |
  Rat   258 LKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIRLRGEFDGTVTFHHPVLPARSIQPYQIPLAGP 322

  Fly   316 SLSPDGQILQCELYSTHWVLFQPNIVIDAKLGCMWFLNLCIEPLCQLISDRIRLTEFLLQRSNGK 380
            :...:...:.|:|||:.|::|||:|:|.|..|.:|.|.:.::|:..|:.|:.||.:|||||...|
  Rat   323 AAVTNQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQVKLQPIVNLLPDKGRLMDFLLQRKECK 387

  Fly   381 QMLLKVIGQLVDDQYKGTLLPVLETIFSRINKIYASWVQLELQNQTAQPSNVKTTTLKQSTPPI- 444
            .::|.|..|::.:..:.| |||:.|:|.::|..|..::..|.....|..:.     ..:|.||:
  Rat   388 AVVLSVCSQMLSESDRAT-LPVIATVFDKLNHEYKKYLDAEQSYTMAVEAG-----QSRSNPPLK 446

  Fly   445 ------VLIEQLDMVQIFQRIARRPYTE----------SILMLYLQSLNKFNIAAQEELSKMIIS 493
                  .:::|.|   ::..:. .|:.|          ::||.|::|||:|.|..|..|.:::|.
  Rat   447 RPVRTQAVVDQSD---VYTHVL-SPFVENKETPPKFVIAVLMEYIRSLNQFQIPVQHYLHELVIK 507

  Fly   494 ELISNRSFDTLRRLVSYSMLLESKSVACFLLSHSNVDTAISQVAIDMLGRIE-AHEIIIEVMLGQ 557
            .|:.:..|..|.:.:.|.:|.:||.:||.|||..:......|:::|||.|:. |::.|:||:|.:
  Rat   508 TLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSK 572

  Fly   558 GKVIDALRLAKNSMGLEKVPARKFLEAAHKTKDDLIFHSVYRFFQMRNLKLYETLSFPKAEQCTE 622
            .:|:.|||..:...|.:.:.|||||:||.:|.|.::|::::|||:.||.:|....:|...|.|.|
  Rat   573 HQVLAALRFIRGIGGHDNISARKFLDAAKQTDDVMLFYTIFRFFEQRNQRLRGNPNFTPGEHCEE 637

  Fly   623 FIQHYNNTF 631
            .:..:...|
  Rat   638 HVAFFKQAF 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bulli	NP_648047.2	Mic1	461..617	CDD:429257	57/166 (34%)
Rmc1	NP_001009638.1	Mic1	475..632	CDD:429257	55/156 (35%)