Protein Alignment CG8270 and Y50D4A.4

DIOPT Version :9

• Sequence 1: NP_648047.2
• Gene: CG8270 / 38734
• FlyBaseID: FBgn0035703
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_503392.3
• Gene: Y50D4A.4 / 178616
• WormBaseID: WBGene00021738
• Length: 628
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 156/616 - (25%)
• Similarity: 282/616 - (45%)
• Gaps: 78/616 - (12%)

  Fly     6 GIHYIELTPNPIRFDAVSQLTNVFFDDSNKQIFAVRSGGATGVVVKGPGSPDDVVISFCMSDRGG 70
            |..:|...|:....|  ..:|..|||.|:::|..:|:.||.|:..|  ...:|.:::....|||.
 Worm     5 GASFIPFEPDRSSHD--GNITRNFFDCSSQRICTMRNNGALGLTSK--SLKNDKIMNVRTKDRGE 65

  Fly    71 AIRSIKFSPDNQILAVQRKENSVEFICFQGDQP--LLQDIITHQVKTLIHGFVWVHNREVALISN 133
            . .::|||||.::.|:||...:.:.:..:..:.  .|:..:..:.|..:....||.|.::.|::|
 Worm    66 P-STVKFSPDGRLCAMQRTPTTADVVFLEKTETSLCLELTVNTKSKEPLLAVEWVTNNQLLLVNN 129

  Fly   134 TGVEVYTVVPEKRQVRSVKSLSIGIKWFAWCCDANVALLCTSEGNS-LIPVLVKQKVITKLP--K 195
            ...|:..:..:|:..:.:|:.::...|..:...:.:.|:...:..| |.|.:|.....|::.  :
 Worm   130 HSAELLYINEDKKSSKLLKATNVNAAWAIYYAPSQLLLIANGQSCSYLQPFVVTHSQFTRMKGFE 194

  Fly   196 VDLGN--PSRDVQESKVTLGQVYGVLAVLILQ---SNSTT-GLMEVEVHLLNGPGLAPRKCHVLR 254
            ||.|.  ...:..|....:..:||.:.||:.:   .|:|. .|.|:......||...    |.|.
 Worm   195 VDFGGSISKENFLEKDAAIATIYGRVYVLVFKYSNRNATVLDLYELPFDAATGPSFK----HSLI 255

  Fly   255 LSLLGRFAINTVDNLIVVHHQASGTSLLFDISLPGEVINEITYHTPITPGRSIKPFGLKLPSLSP 319
            |...|...|:.:|||:|||||||..||:|||.:.             :|.:|..|..:......|
 Worm   256 LGFNGGCGIHVIDNLVVVHHQASQKSLIFDIRVS-------------SPSKSHSPLVVTTIESHP 307

  Fly   320 DGQILQCELYSTHWVLFQPNIVIDAKLGCMWFLNLCIEPLCQLISDRIRLTEFLLQRSNGKQMLL 384
            ..|.... ||:..|..|.|:||||:..|.|:.:.|..|.....|:|:..:.|:|.:|||.|::.:
 Worm   308 QHQPPPA-LYTNFWFTFLPDIVIDSSGGVMYSIRLKNEHAQLEIADKQTMLEYLARRSNEKKLFV 371

  Fly   385 KVIGQLVDDQYKGTLLPVLET---IFSRINKIYASWVQLELQNQTAQPS--NVKTTTLK------ 438
            .            |||..|:.   ...:|.|::|....:..::..::.|  |...::.|
 Worm   372 T------------TLLACLKARALSLRQIRKVFAMLTGVTGKSSASENSVENGSGSSQKPVLDCE 424

  Fly   439 ------------QSTPPIVLIEQLDMVQIFQRIARRPYTESILMLYLQSLNKFNIAAQEELSKMI 491
                        ||:..|.|.|::.:.:        .|..:|::.||:||....|..:..|.:|:
 Worm   425 KYASLAVTQQEMQSSVLIPLREEVSLPE--------SYVANIMLQYLRSLFDAEITPEAYLIEMV 481

  Fly   492 ISELISNRSFDTLRRLVSYSMLLESKSVACFLLSHSNVDTAISQVAIDMLGRIEAHEIIIEVMLG 556
            :..|........|:::|:|.::.:||.:|..|||:....:.:.|..:|:|.|.:|.:.|:||||.
 Worm   482 VETLAEAGEMSKLQQIVTYRVINDSKPLAFLLLSYEARCSTLFQSGVDILARNKASDEIVEVMLE 546

  Fly   557 QGKVIDALRLAKNSMGLEKVPARKFLEAAHK 587
            :.:::||.|.. :...|......|.:|||::
 Worm   547 KKQIVDAFRFI-DVRNLNDALIPKVVEAANQ 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8270	NP_648047.2	Mic1	461..616	CDD:284457	37/127 (29%)
Y50D4A.4	NP_503392.3	Mic1	451..606	CDD:369179	37/135 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167525
Domainoid	1	1.000	129	1.000	Domainoid score	I3288
eggNOG	1	0.900	-	-		E1_KOG2377
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8341
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2744
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59981
OrthoDB	1	1.010	-	-		D191938at33208
OrthoFinder	1	1.000	-	-		FOG0006644
OrthoInspector	1	1.000	-	-		oto20363
orthoMCL	1	0.900	-	-		OOG6_104796
Panther	1	1.100	-	-	LDO	PTHR12897
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4196
SonicParanoid	1	1.000	-	-		X5651
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800