Protein Alignment CG10147 and ZNF212

DIOPT Version :9

• Sequence 1: NP_001261477.1
• Gene: CG10147 / 38733
• FlyBaseID: FBgn0035702
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_036388.2
• Gene: ZNF212 / 7988
• HGNCID: 13004
• Length: 495
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 79/344 - (22%)
• Similarity: 111/344 - (32%)
• Gaps: 127/344 - (36%)

  Fly   109 EELLLEPPEMIICDTNL-SAQNTPIVAEQAPPTLVFHTFTENVQQPPETEKKALEEP-----PLT 167
            |:..|.|.:     |.| ..|.:.::.|..|                  ....||||     |.:
Human   240 EQAFLSPEQ-----TELWGGQGSSVLLETGP------------------GDSTLEEPVGSRVPSS 281

  Fly   168 --TYKCDLCADEFREEKRLILHKKEHQGHML-------YHCTEPGCEEAFNRFENLRQHELEHSE 223
              |..|    .:.:..:::.|.::..||..|       |.|:|  ||..|...:.|..|...||.
Human   282 SRTVGC----PKQKSHRQVQLDQECGQGLKLKKDTSRPYECSE--CEITFRYKQQLATHLRSHSG 340

  Fly   224 VGMRFVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEFCGRVFKTGSALSQHRFTHGDQL 288
            .|.   |..|......|.:..||....||       |.|.|:.|.|.|
Human   341 WGS---CTPEEPEESLRPRPRLKPQTKKA-------KLHQCDVCLRSF----------------- 378

  Fly   289 VLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHI------NYHTLE 347
                :|               |:.::.||                    |.|:      ..|..|
Human   379 ----SC---------------KVSLVTHQ--------------------RCHLQEGPSAGQHVQE 404

  Fly   348 RTWSCKDCPKVCNSSTSLKKHIRAIHEKAR-DYACSYCEKKFATTDTRKYHEMTHTGEKNFECHV 411
            |.     .|   ||..:|..||.  ..|:| ...|.||.|.|:.......|:..||||:.:.|..
Human   405 RF-----SP---NSLVALPGHIP--WRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTE 459

  Fly   412 CGKKFIQPSALRTHRKVHE 430
            |.|.|:|...|..|:|:|:
Human   460 CEKSFVQKQHLLQHQKIHQ 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368	2/19 (11%)
		zf-C2H2_8	199..287	CDD:292531	23/87 (26%)
		C2H2 Zn finger	199..221	CDD:275368	7/21 (33%)
		C2H2 Zn finger	230..253	CDD:275368	6/22 (27%)
		C2H2 Zn finger	264..284	CDD:275368	4/19 (21%)
		C2H2 Zn finger	294..316	CDD:275368	2/21 (10%)
		C2H2 Zn finger	324..344	CDD:275368	2/25 (8%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		C2H2 Zn finger	409..429	CDD:275368	8/19 (42%)
ZNF212	NP_036388.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		KRAB_A-box	142..180	CDD:143639
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..290		8/47 (17%)
		C2H2 Zn finger	318..338	CDD:275370	7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..361		7/26 (27%)
		COG5048	<367..479	CDD:227381	42/178 (24%)
		C2H2 Zn finger	371..391	CDD:275368	9/75 (12%)
		C2H2 Zn finger	429..449	CDD:275368	6/19 (32%)
		zf-C2H2	429..449	CDD:306579	6/19 (32%)
		zf-H2C2_2	441..466	CDD:316026	9/24 (38%)
		C2H2 Zn finger	457..477	CDD:275368	8/19 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..495		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100