DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10147 and ZNF692

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_011542525.1	Gene:	ZNF692 / 55657	HGNCID:	26049	Length:	625	Species:	Homo sapiens

Alignment Length:	181	Identity:	50/181 - (27%)
Similarity:	73/181 - (40%)	Gaps:	34/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 IGKPLKTHM--CEF--CGRVFKTGSALSQH-RFTHGDQLVLPYACELPECSMRFYSTEKLKIHMM 314
            |.|..|..:  |:|  |||:|.....|:.| ::.|..|  ..::|..|.|...|...:.||.||.
Human   425 IRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQ--KSFSCPEPACGKSFNFKKHLKEHMK 487

  Fly   315 RHQGIKNFSCPYCGLKKTTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARDY 379
            .|...:::.|.:|.....|.:.|.:|...||.|:...|:.|...|....||..|
Human   488 LHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWH----------- 541

  Fly   380 ACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPSALRTHR-KVH 429
                 ::|.|.|          .....|.|..|||:|.:|.::..|| |.|
Human   542 -----QRKHAET----------VAALRFPCEFCGKRFEKPDSVAAHRSKSH 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368
		zf-C2H2_8	199..287	CDD:292531	12/36 (33%)
		C2H2 Zn finger	199..221	CDD:275368
		C2H2 Zn finger	230..253	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368	8/22 (36%)
		C2H2 Zn finger	294..316	CDD:275368	8/21 (38%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	3/19 (16%)
		C2H2 Zn finger	409..429	CDD:275368	9/20 (45%)
ZNF692	XP_011542525.1	zf-C2H2	465..489	CDD:278523	8/23 (35%)
		C2H2 Zn finger	467..489	CDD:275368	8/21 (38%)
		COG5048	490..>591	CDD:227381	28/114 (25%)
		zf-C2H2	495..517	CDD:278523	5/21 (24%)
		C2H2 Zn finger	497..517	CDD:275368	5/19 (26%)
		zf-H2C2_2	509..534	CDD:290200	8/24 (33%)
		C2H2 Zn finger	525..545	CDD:275368	6/35 (17%)
		C2H2 Zn finger	556..577	CDD:275368	9/20 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100