DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10147 and Zfp652

DIOPT Version :9

Sequence 1:NP_001261477.1 Gene:CG10147 / 38733 FlyBaseID:FBgn0035702 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_001073676.1 Gene:Zfp652 / 497984 RGDID:1566329 Length:608 Species:Rattus norvegicus


Alignment Length:457 Identity:109/457 - (23%)
Similarity:171/457 - (37%) Gaps:130/457 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 IIADNKWRSKSL-VTWKKIDRRKP-----VYEVDEDEE--EELELEELLLEPPEMIICDTNLSAQ 128
            ::||:|.....| .|.::...|:|     |:.|.||.|  ::.|.||.:....|.||.:.||:.|
  Rat    61 VLADSKMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQ 125

  Fly   129 NTPI------VAEQAPPTLVFHTFTENVQQP---------------------------------- 153
            ...:      |:.|:..|.|..|.:|..::.                                  
  Rat   126 TLNVSKGEKGVSSQSKETPVLKTSSEEEEEETEEDATDNSSDYGENGRQKKKEKQVEKVRVTQRR 190

  Fly   154 ----------------------------PETEKKALEEP--PLTTYKCDLCADEFREEKRLILHK 188
                                        |:.:|:|.:||  |:...|||        ||..:..:
  Rat   191 TRRAASVAAATTSPTPRTTRGRRKSAELPKRKKRAAKEPKAPVQKAKCD--------EKETLTCE 247

  Fly   189 KEHQGHMLYHCTEPGCEEAFNRFENLRQH-ELEH------SEVGMRFVCEEE------------- 233
            |              |...||....|.:| .:.|      .:.|.:||.|.|             
  Rat   248 K--------------CPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNI 298

  Fly   234 ---GCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEFCGRVFKTGSALSQHRFTHGDQLVLPYACE 295
               .||:.::...||..|....|  |...|...||.|.:.|.|.:.:.:|...|...  :|:.||
  Rat   299 QCVSCNKSFKKLWSLHEHIKIVH--GYAEKKFACEICEKKFYTMAHVRKHMVAHTKD--MPFTCE 359

  Fly   296 LPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHINYHTLERTWSCKDCPKVCN 360
              .|...|..:..||:|.::|.|.|.|.|..|..:...|.:||.|::.|...:.:.|:.|.|..|
  Rat   360 --TCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFN 422

  Fly   361 SSTSLKKHIRAIHEKARDYACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPSALRTH 425
            ......:|::. |...:.:.|..|.|.|.:....|.|..||||||.:.|.|||::|...:.|:.|
  Rat   423 MKQYFDEHMKT-HTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAH 486

  Fly   426 RK 427
            ::
  Rat   487 KE 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10147NP_001261477.1 zf-AD 7..80 CDD:214871 3/7 (43%)
C2H2 Zn finger 171..191 CDD:275368 5/19 (26%)
zf-C2H2_8 199..287 CDD:292531 26/110 (24%)
C2H2 Zn finger 199..221 CDD:275368 5/22 (23%)
C2H2 Zn finger 230..253 CDD:275368 7/38 (18%)
C2H2 Zn finger 264..284 CDD:275368 6/19 (32%)
C2H2 Zn finger 294..316 CDD:275368 7/21 (33%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
C2H2 Zn finger 352..373 CDD:275368 5/20 (25%)
C2H2 Zn finger 381..401 CDD:275368 6/19 (32%)
C2H2 Zn finger 409..429 CDD:275368 7/19 (37%)
Zfp652NP_001073676.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 60..234 33/172 (19%)
C2H2 Zn finger 246..265 CDD:275368 6/32 (19%)
C2H2 Zn finger 273..292 CDD:275368 5/18 (28%)
C2H2 Zn finger 300..320 CDD:275368 5/19 (26%)
C2H2 Zn finger 330..350 CDD:275368 6/19 (32%)
C2H2 Zn finger 358..378 CDD:275368 7/21 (33%)
SFP1 <380..463 CDD:227516 23/83 (28%)
C2H2 Zn finger 386..406 CDD:275368 6/19 (32%)
C2H2 Zn finger 414..434 CDD:275368 5/20 (25%)
COG5048 438..>487 CDD:227381 18/48 (38%)
C2H2 Zn finger 442..462 CDD:275368 6/19 (32%)
C2H2 Zn finger 470..486 CDD:275368 6/15 (40%)
Mediates interaction with CBFA2T3. /evidence=ECO:0000250 497..608
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 540..589
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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