DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10147 and CG14655

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	81/336 - (24%)
Similarity:	117/336 - (34%)	Gaps:	78/336 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 PPETEKKALEE-------PPLTT---YKCDLCADEFREEKRLILHKKEHQGHMLYHCTEPGCEEA 207
            ||:...|....       ||:.|   ..||:|...||..:...:|.:      |.|....|
  Fly    86 PPKRRAKRTRSKPVVPTPPPVRTTPPAHCDICEFSFRNTELRDMHVR------LVHENAEG---- 140

  Fly   208 FNRFENLRQHELEHSEVGMR-FVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLK----------- 260
                 ..:|.|.:..|.... :.|..  |::.:|.|.||:.|....|.:|.|..
  Fly   141 -----EPKQKEPQQKEPDQEPYKCHL--CSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPT 198

  Fly   261 ----------THMCEFCGRVFKT-------GS----ALSQHRFTHGDQLVLPYACELPECSMRFY 304
                      |.....|.|:..|       |:    ..||.....|...:|..:...||...
  Fly   199 PASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCTASQPYALSGALSMLQQSPSSPESGT--- 260

  Fly   305 STEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHI 369
            :|.||            :.|..|....|||..|:.|...||.|..::|:.|.:......|..||:
  Fly   261 ATPKL------------WECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHL 313

  Fly   370 RAIHEKARDYACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPSALRTHRKVHESGDN 434
             ..|.:.:.:.|..|.:.|....|...|:..|:|||.|:|.||||.|.|..:...|.::|..  .
  Fly   314 -LYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTG--V 375

  Fly   435 QQTACALLQLT 445
            ....|.|.|.|
  Fly   376 MPYKCELCQKT 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368	6/19 (32%)
		zf-C2H2_8	199..287	CDD:292531	22/120 (18%)
		C2H2 Zn finger	199..221	CDD:275368	3/21 (14%)
		C2H2 Zn finger	230..253	CDD:275368	7/22 (32%)
		C2H2 Zn finger	264..284	CDD:275368	6/30 (20%)
		C2H2 Zn finger	294..316	CDD:275368	5/21 (24%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	8/19 (42%)
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		zf-H2C2_2	281..304	CDD:290200	7/22 (32%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		zf-H2C2_2	339..361	CDD:290200	12/21 (57%)
		C2H2 Zn finger	352..372	CDD:275368	8/19 (42%)
		zf-H2C2_2	364..389	CDD:290200	6/25 (24%)
		C2H2 Zn finger	380..396	CDD:275368	4/7 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100