DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10147 and D19B

DIOPT Version :10

Sequence 1:NP_648046.1 Gene:CG10147 / 38733 FlyBaseID:FBgn0035702 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_477297.1 Gene:D19B / 38717 FlyBaseID:FBgn0022699 Length:774 Species:Drosophila melanogaster


Alignment Length:514 Identity:148/514 - (28%)
Similarity:226/514 - (43%) Gaps:90/514 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 CRVCSSDVARDDEAYNLLHHPYLAVKFSECTNLVVDPDDQDILPSEICSECYELLEKFHSFRALC 71
            ||.|.|.| .|..||:|...|.||.|...||:|.|  :..|..|..:|:.|:..|...|.|:..|
  Fly    13 CRTCLSTV-DDSAAYDLFRVPGLAKKLCVCTSLSV--EQADGFPKNLCNVCFSKLNDLHDFQKQC 74

  Fly    72 I---------IADNKWRSKS--------------------------LVTWK--KIDRRKPVYEVD 99
            :         :|.|.:..::                          |:..|  .|:..:.|:::.
  Fly    75 VDSVQKFQDLVASNAFACQTNFDVLDTSAAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKML 139

  Fly   100 EDEEEELELEELLLEPP---------------EMIICDTNLSAQNTPIVAEQA------------ 137
            |..|:|:|..|:.:|.|               ..:..|..:|:.:...:|:::            
  Fly   140 ESVEKEVEEVEMEMEQPFGRVSQDDSFESGNDNDLDADFQISSDDDIPLAQRSRRGATRGSKAKG 204

  Fly   138 PPTLVFHTFTENVQQPPET-----------EKKALEEPPLT------TYKCDLCADEFREEKRLI 185
            .|........|..::..||           :|...:..|.|      ...|.:|..:|::..|..
  Fly   205 KPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYE 269

  Fly   186 LHKKEHQGHMLYHCTEPGCEEAFNRFENLRQH-ELEHSEVGMRFVCEEEGCNRMYRHKASLKYHQ 249
            .|.|.|...:.:.||...|.:.|.....||.| |..|:|......|..||||:.:.....|.:|.
  Fly   270 EHMKHHNDLLPFQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHM 334

  Fly   250 SKAHDIGKPLKTHMCEFCGRVFKTGSALSQHRFTH-GDQLVLPYACELPECSMRFYSTEKLKIHM 313
            .:.|.:..|.:...|..|.:||:..:||.:|.:.| |::  ||:|||:  |..||.....|:.|:
  Fly   335 KRVHKVDTPQRDFPCTECEKVFRCPTALKKHMYKHTGEE--LPFACEI--CGKRFPINSVLRDHL 395

  Fly   314 MRHQGIKNFSCPYCGLKKTTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARD 378
            :||.||||..|||||:.|||:.|...||..||.|:.:.|:.|....::..:|..|::.:|||.:|
  Fly   396 LRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKD 460

  Fly   379 YACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPSALRTHRKVHESGDNQQT 437
            :||.||.|.|..:...|.||.:|||||..||.:|||.|:....|..|.|.||..|..:|
  Fly   461 FACQYCGKTFGKSHACKIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKT 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10147NP_648046.1 zf-AD 7..80 CDD:214871 27/81 (33%)
C2H2 Zn finger 171..191 CDD:275368 6/19 (32%)
C2H2 Zn finger 199..221 CDD:275368 8/22 (36%)
SFP1 <228..284 CDD:227516 16/55 (29%)
C2H2 Zn finger 230..253 CDD:275368 7/22 (32%)
C2H2 Zn finger 264..284 CDD:275368 7/19 (37%)
C2H2 Zn finger 294..316 CDD:275368 7/21 (33%)
C2H2 Zn finger 324..344 CDD:275368 11/19 (58%)
C2H2 Zn finger 352..373 CDD:275368 4/20 (20%)
C2H2 Zn finger 381..401 CDD:275368 8/19 (42%)
C2H2 Zn finger 409..429 CDD:275368 8/19 (42%)
D19BNP_477297.1 zf-AD 12..83 CDD:214871 25/72 (35%)
C2H2 Zn finger 255..275 CDD:275368 6/19 (32%)
SFP1 <266..365 CDD:227516 29/98 (30%)
C2H2 Zn finger 283..335 CDD:275368 17/51 (33%)
C2H2 Zn finger 318..338 CDD:275368 6/19 (32%)
COG5048 <347..512 CDD:227381 70/168 (42%)
C2H2 Zn finger 349..369 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 7/21 (33%)
C2H2 Zn finger 406..426 CDD:275368 11/19 (58%)
C2H2 Zn finger 434..455 CDD:275368 4/20 (20%)
C2H2 Zn finger 463..483 CDD:275368 8/19 (42%)
C2H2 Zn finger 491..511 CDD:275368 8/19 (42%)
C2H2 Zn finger 586..607 CDD:275368
C2H2 Zn finger 615..635 CDD:275368
zf-H2C2_2 627..652 CDD:463886
C2H2 Zn finger 643..663 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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