DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10147 and CG8944

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	83/348 - (23%)
Similarity:	120/348 - (34%)	Gaps:	125/348 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 EQAPPTLVFHTFTENVQQPPETEKKALEEPPLT--TYKCDLCADEFREEKRLILHKKEHQG---H 194
            :..||....|. .|.||...|.:...|...|..  .|.|::|:.:|...:....||:.|.|   .
  Fly   469 DDIPPFKCAHC-PEIVQTLRELDLHMLTHQPSLGGGYYCNICSIQFHNAQEFDNHKQLHLGGVTE 532

  Fly   195 MLYHCTEPGCEEAF----NRFENLRQHE---------LEHS---------EVGMRFVCEE---EG 234
            :.::|..  |..:|    |..|:||:|.         |.||         |:|:.  .||   .|
  Fly   533 IKFNCEL--CTASFREKANYDEHLRRHNEELFLPSLALNHSIMEGGLGDDEIGVE--GEESRGSG 593

  Fly   235 CNRMYRHKASLKYHQSKA-----------------------HDIGKPLKTHMCEFCGRVFKTGSA 276
            ..|..||.|       ||                       .||.||   :.|:.|.|.|.|...
  Fly   594 SRRKRRHAA-------KATDDMVDDDDRIGGGGGGGSGGGGTDIAKP---YGCDVCRRSFATPGH 648

  Fly   277 LSQHRFTHGDQLVLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHI 341
            |:.||..|.|:....|.|:.|:|:..|.:...|..|:.:|...:.|.|..||  ||.|
  Fly   649 LNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFEHLKQHYSNEEFKCDICG--KTFK------- 704

  Fly   342 NYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARDYACSYCEKKFATTDTRKYHEMTHTGEKN 406
                               |:.:|:.| :.||:|.:.|.
  Fly   705 -------------------STKNLQNH-KQIHDKIKRYV-------------------------- 723

  Fly   407 FECHVCGKKFIQPSALRTHRKVH 429
              |.:||..|.|.:.|..|::.|
  Fly   724 --CQICGSAFAQAAGLYLHKRRH 744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368	5/19 (26%)
		zf-C2H2_8	199..287	CDD:292531	35/135 (26%)
		C2H2 Zn finger	199..221	CDD:275368	9/34 (26%)
		C2H2 Zn finger	230..253	CDD:275368	9/48 (19%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		C2H2 Zn finger	294..316	CDD:275368	6/21 (29%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	3/20 (15%)
		C2H2 Zn finger	381..401	CDD:275368	0/19 (0%)
		C2H2 Zn finger	409..429	CDD:275368	7/19 (37%)
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738	0/2 (0%)
		C2H2 Zn finger	476..496	CDD:275368	6/20 (30%)
		C2H2 Zn finger	506..526	CDD:275368	5/19 (26%)
		C2H2 Zn finger	537..557	CDD:275368	7/21 (33%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
		zf-C2H2_8	639..712	CDD:292531	26/100 (26%)
		C2H2 Zn finger	666..688	CDD:275368	6/21 (29%)
		zf-C2H2	694..716	CDD:278523	10/50 (20%)
		C2H2 Zn finger	696..716	CDD:275368	9/48 (19%)
		zf-H2C2_2	708..733	CDD:290200	10/53 (19%)
		C2H2 Zn finger	724..744	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100