DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10147 and Zfp691

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001101438.1	Gene:	Zfp691 / 313548	RGDID:	1308150	Length:	283	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	69/276 - (25%)
Similarity:	102/276 - (36%)	Gaps:	78/276 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 PETEKKALEEPPLTTYKCDLCADEFREEKRLILHKKEHQGHMLYHCTEPGCEEAFNRFENLRQHE 218
            |||::|     |.|   |..|...|.....|..|::.|.|...|.|:|  |.::|:|..|..:||
  Rat    76 PETDEK-----PFT---CAQCGKAFNNTSNLRTHQRIHTGEKPYKCSE--CGKSFSRSSNRIRHE 130

  Fly   219 LEHSEVGMRFVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEFCGRVFKTGSALSQHRFT 283
            ..|.| ...:.|..  |...:|.::.|..||.  ..:|:  :.:.|:.||:.|...|.|:.|..|
  Rat   131 RIHLE-EKHYQCAR--CQESFRRRSDLTTHQQ--DHLGQ--RPYRCDICGKSFSQSSTLAVHHRT 188

  Fly   284 HGDQLVLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHINYHTLER 348
            |.:.  .||.|  .||...|.::....:|...|.|
  Rat   189 HLEP--APYIC--CECGKSFSNSSSFGVHHRTHTG------------------------------ 219

  Fly   349 TWSCKDCPKVCNSSTSLKKHIRAIHEKARDYACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCG 413
                                       .|.|.|:.|.:.|:.......|:.||.||:.:.|.:||
  Rat   220 ---------------------------ERPYECTECGRTFSDISNFGAHQRTHRGERPYRCTLCG 257

  Fly   414 KKFIQPSALRTHRKVH 429
            |.|.:.|.|..|:|.|
  Rat   258 KHFSRSSNLIRHQKTH 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368	5/19 (26%)
		zf-C2H2_8	199..287	CDD:292531	26/87 (30%)
		C2H2 Zn finger	199..221	CDD:275368	8/21 (38%)
		C2H2 Zn finger	230..253	CDD:275368	6/22 (27%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		C2H2 Zn finger	294..316	CDD:275368	5/21 (24%)
		C2H2 Zn finger	324..344	CDD:275368	0/19 (0%)
		C2H2 Zn finger	352..373	CDD:275368	0/20 (0%)
		C2H2 Zn finger	381..401	CDD:275368	4/19 (21%)
		C2H2 Zn finger	409..429	CDD:275368	9/19 (47%)
Zfp691	NP_001101438.1	COG5048	<73..234	CDD:227381	54/235 (23%)
		C2H2 Zn finger	85..105	CDD:275368	5/19 (26%)
		zf-H2C2_2	97..122	CDD:290200	9/26 (35%)
		C2H2 Zn finger	113..133	CDD:275368	8/21 (38%)
		C2H2 Zn finger	141..161	CDD:275368	6/23 (26%)
		zf-H2C2_2	153..178	CDD:290200	8/28 (29%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)
		C2H2 Zn finger	197..217	CDD:275368	5/21 (24%)
		zf-H2C2_2	212..233	CDD:290200	7/77 (9%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		zf-C2H2	251..273	CDD:278523	9/21 (43%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000