DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10147 and ZNF660

DIOPT Version :9

Sequence 1:NP_001261477.1 Gene:CG10147 / 38733 FlyBaseID:FBgn0035702 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_775929.2 Gene:ZNF660 / 285349 HGNCID:26720 Length:331 Species:Homo sapiens


Alignment Length:316 Identity:96/316 - (30%)
Similarity:140/316 - (44%) Gaps:35/316 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   147 TENVQQPPETEKKALEEPPLT--------TYKCDLCADEFREEKRLILHKKEHQGHMLYHCTEPG 203
            ||...|..|.:.....:|...        .|.|..|...|.:...|.:|::.|.|...|.|.|  
Human    20 TEGSDQESEKDNSQCCDPATNERVQAEKRQYVCTECGKAFSQSANLTVHERIHTGEKPYKCKE-- 82

  Fly   204 CEEAFNRFENLRQHELEHSEVGMR-FVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEFC 267
            |.:||:...||..|...|:  |:: :.|.|  |.:.:..|:.|..||.    |....||:.|:.|
Human    83 CGKAFSHSSNLVVHRRIHT--GLKPYTCSE--CGKSFSGKSHLIRHQG----IHSGEKTYECKEC 139

  Fly   268 GRVFKTGSAL-SQHRFTHGDQLVLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKK 331
            |:.|...|.| |.||...|::   ||:|  .||...|..:..|..|...|:|.|.:.|..||...
Human   140 GKAFSRSSGLISHHRVHTGEK---PYSC--IECGKAFSRSSNLTQHQRMHRGKKVYKCKECGKTC 199

  Fly   332 TTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARDYACSYCEKKFATTDTRKY 396
            .:..::..|...||.|:.:.|.:|.|......:|.:|.| :|.:.:.|.|:.|.|.|.:......
Human   200 GSNTKIMDHQRIHTGEKPYECDECGKTFILRKTLNEHQR-LHRREKPYKCNECGKAFTSNRNLVD 263

  Fly   397 HEMTHTGEKNFECHVCGKKFIQPSA----LRTHR-----KVHESGDNQQTACALLQ 443
            |:..|||||.::|:.|||.|.|.|.    ||||.     |..|.|...:.:..|:|
Human   264 HQRVHTGEKPYKCNECGKTFRQTSQVILHLRTHTKEKPYKCSECGKAYRYSSQLIQ 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10147NP_001261477.1 zf-AD 7..80 CDD:214871
C2H2 Zn finger 171..191 CDD:275368 5/19 (26%)
zf-C2H2_8 199..287 CDD:292531 30/89 (34%)
C2H2 Zn finger 199..221 CDD:275368 8/21 (38%)
C2H2 Zn finger 230..253 CDD:275368 7/22 (32%)
C2H2 Zn finger 264..284 CDD:275368 9/20 (45%)
C2H2 Zn finger 294..316 CDD:275368 6/21 (29%)
C2H2 Zn finger 324..344 CDD:275368 4/19 (21%)
C2H2 Zn finger 352..373 CDD:275368 6/20 (30%)
C2H2 Zn finger 381..401 CDD:275368 5/19 (26%)
C2H2 Zn finger 409..429 CDD:275368 12/28 (43%)
ZNF660NP_775929.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35 4/14 (29%)
C2H2 Zn finger 52..72 CDD:275368 5/19 (26%)
zf-H2C2_2 64..89 CDD:316026 10/26 (38%)
C2H2 Zn finger 80..100 CDD:275368 8/21 (38%)
COG5048 <107..294 CDD:227381 63/198 (32%)
C2H2 Zn finger 108..128 CDD:275368 7/25 (28%)
C2H2 Zn finger 136..156 CDD:275368 9/19 (47%)
C2H2 Zn finger 164..184 CDD:275368 6/21 (29%)
C2H2 Zn finger 192..207 CDD:275368 3/14 (21%)
C2H2 Zn finger 220..240 CDD:275368 6/20 (30%)
C2H2 Zn finger 248..268 CDD:275368 5/19 (26%)
C2H2 Zn finger 276..296 CDD:275368 9/19 (47%)
C2H2 Zn finger 304..324 CDD:275368 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.