DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10147 and Zfp940

DIOPT Version :9

Sequence 1:NP_001261477.1 Gene:CG10147 / 38733 FlyBaseID:FBgn0035702 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_776099.1 Gene:Zfp940 / 233057 MGIID:2446235 Length:566 Species:Mus musculus


Alignment Length:491 Identity:126/491 - (25%)
Similarity:193/491 - (39%) Gaps:99/491 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 AYNLLHHPYLAVKFS----ECTNLVVDPDDQDILPSEICSECYELLEKF-------HSFRAL--- 70
            |..|:....:||.||    ||.:|     ||..|..::..|.|..|...       |.|..|   
Mouse     2 AQRLMTFRDVAVDFSPEEWECLSL-----DQRSLYRDVMLESYSHLVSVGLFVYRPHLFSLLEKG 61

  Fly    71 ----CIIAD--------------NKWRSKSLVTWKKIDRR----------------------KPV 95
                .|:.|              ||.......|::::.:|                      |..
Mouse    62 QDPWMILRDETRGPYPDIDFSSQNKKFLGKPSTYEELSQREMKEYFRKRSLEDFCFGDGWDGKNQ 126

  Fly    96 YEVDEDEEEELEL----EELLL----------------EPPEMIICDTNLSAQNTPIVAEQAPPT 140
            ::..:::|...:|    |::|.                |....|.|:..|:.::..|:.:..||.
Mouse   127 FQTHQNQEYFKQLAVAYEKVLTVNQGIVFNNHQRLNAGEKATEIQCEKALTVESDRILPQLTPPG 191

  Fly   141 LVFHTFTE-NVQQPPETEKKALEEP--PLTTYKCDLCADEFREEKRLILHKKEHQGHMLYHCTEP 202
            ...|...| .....||:|:...:..  |.|..:.......|.....::...:.|.|...|.|.| 
Mouse   192 NKVHKDKECGDTSAPESERTHCQRAHCPQTPQQGKESGGPFGLPSGILGLPQGHTGEKSYDCKE- 255

  Fly   203 GCEEAFNRFENLRQHELEHSEVGMR-FVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEF 266
             |.::|....||.:|...|:  |.| :.|  .||.:.:..|:.|..|| |.| .||  |.::|..
Mouse   256 -CGKSFTLKSNLTRHRRIHT--GERPYTC--HGCGKAFTQKSHLMSHQ-KIH-TGK--KAYVCGV 311

  Fly   267 CGRVFKTGSALSQHRFTH---GDQLVLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCG 328
            ||:.|...|:|:.|:..|   .|.....|.|:  :|...|.....|..|...|.|.|.|.|.:||
Mouse   312 CGKAFHCDSSLTSHQNIHYHAADAGKKAYECK--KCGKDFDCHSGLIDHQKVHTGEKPFKCKHCG 374

  Fly   329 LKKTTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARDYACSYCEKKFATTDT 393
            ......:.||.|...|:..:::.||:|.|..|..::|.:|.| :|...|.|.|..|.|.|:....
Mouse   375 RLFRFHSHLRAHTRIHSGVKSYDCKECGKSFNLRSNLMRHHR-VHTGERPYTCHGCGKAFSQKSH 438

  Fly   394 RKYHEMTHTGEKNFECHVCGKKFIQPSALRTHRKVH 429
            ...|:..|||||.:.|.||||.|.:.|:|.:|:.:|
Mouse   439 LTSHQKIHTGEKAYVCGVCGKAFSRGSSLTSHQNIH 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10147NP_001261477.1 zf-AD 7..80 CDD:214871 22/91 (24%)
C2H2 Zn finger 171..191 CDD:275368 1/19 (5%)
zf-C2H2_8 199..287 CDD:292531 30/91 (33%)
C2H2 Zn finger 199..221 CDD:275368 7/21 (33%)
C2H2 Zn finger 230..253 CDD:275368 8/22 (36%)
C2H2 Zn finger 264..284 CDD:275368 7/19 (37%)
C2H2 Zn finger 294..316 CDD:275368 5/21 (24%)
C2H2 Zn finger 324..344 CDD:275368 6/19 (32%)
C2H2 Zn finger 352..373 CDD:275368 8/20 (40%)
C2H2 Zn finger 381..401 CDD:275368 5/19 (26%)
C2H2 Zn finger 409..429 CDD:275368 9/19 (47%)
Zfp940NP_776099.1 KRAB 6..66 CDD:214630 16/64 (25%)
COG5048 <249..437 CDD:227381 64/200 (32%)
C2H2 Zn finger 253..273 CDD:275368 7/21 (33%)
C2H2 Zn finger 281..301 CDD:275368 8/22 (36%)
C2H2 Zn finger 309..329 CDD:275368 7/19 (37%)
C2H2 Zn finger 342..357 CDD:275370 4/16 (25%)
COG5048 <366..524 CDD:227381 40/110 (36%)
C2H2 Zn finger 370..390 CDD:275368 6/19 (32%)
C2H2 Zn finger 398..418 CDD:275368 8/20 (40%)
C2H2 Zn finger 426..446 CDD:275368 5/19 (26%)
C2H2 Zn finger 454..474 CDD:275368 9/19 (47%)
C2H2 Zn finger 487..507 CDD:275368
C2H2 Zn finger 515..535 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.