DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10147 and M03D4.4

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	234	Identity:	66/234 - (28%)
Similarity:	93/234 - (39%)	Gaps:	24/234 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 LYHCTEPGCEEAFNRFENLRQHELEHSEVGMRFVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLK 260
            ||.|.:  |..||:..:.|::||.|..|...:...||:   ||......|...:.|..|
Worm     4 LYLCRD--CSGAFHSLDELQRHEREEHETVEQGDQEED---RMEDDSDELAMIKIKIED------ 57

  Fly   261 THMCEFCGRVFKTGSALSQHRFTHGDQLVL----PYACELPECSMRFYSTEKLKIHMMRHQGIKN 321
               .:|....  ..|.||.:..|..::...    .|.||  :|...|....:|..||..|.|.:.
Worm    58 ---SDFLSDT--DSSQLSMNPTTPSEKSSSGEKGRYECE--DCHEMFAVKRELATHMRIHSGEQP 115

  Fly   322 FSCPYCGLKKTTKNELRLHINYHTLERTWSCKDCPKVCNSSTSLKKHIRAIHEKARDYACSYCEK 386
            .||..||.:..|:..|:.|..:||.||:..|..|.|.......|.:|: .||...|.:.|..|.|
Worm   116 HSCTQCGKEFGTRQLLKKHWMWHTGERSHVCPHCNKAFFQKGHLTQHL-MIHSGGRPHECPQCHK 179

  Fly   387 KFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPSALRTH 425
            .|........|...|. |:.|.|..||:.|::...|..|
Worm   180 TFIFKFDLNRHMKIHQ-ERGFSCQQCGRSFLKQVMLDEH 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368
		zf-C2H2_8	199..287	CDD:292531	21/87 (24%)
		C2H2 Zn finger	199..221	CDD:275368	7/21 (33%)
		C2H2 Zn finger	230..253	CDD:275368	6/22 (27%)
		C2H2 Zn finger	264..284	CDD:275368	4/19 (21%)
		C2H2 Zn finger	294..316	CDD:275368	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	6/17 (35%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	7/21 (33%)
		zf-H2C2_2	102..127	CDD:290200	9/24 (38%)
		C2H2 Zn finger	118..138	CDD:275368	6/19 (32%)
		C2H2 Zn finger	146..166	CDD:275368	5/20 (25%)
		zf-H2C2_2	158..181	CDD:290200	8/23 (35%)
		zf-C2H2	172..194	CDD:278523	5/21 (24%)
		C2H2 Zn finger	174..194	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000