DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10147 and hinf-1

DIOPT Version :9

Sequence 1:	NP_001261477.1	Gene:	CG10147 / 38733	FlyBaseID:	FBgn0035702	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_493579.2	Gene:	hinf-1 / 173348	WormBaseID:	WBGene00009553	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	69/259 - (26%)
Similarity:	107/259 - (41%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 MLYHCTEPGCEEAFNRFENLRQHELEHSE-VG---------------MRFVCEEEGCNRMYRHKA 243
            ||.:|....|...||....|..|...|.: ||               :.|.|:...|.::...||
Worm   243 MLLNCQWEDCGMPFNSLTELFDHVGHHIDGVGDVDRIQQNFSNGDKKVVFPCKWTACTQVADSKA 307

  Fly   244 SLKYHQSKAHDIGKPLKTHMCEFCGRVFKTGSALSQH--RFT---HGDQLVLPYACELPECSMRF 303
            :|:.|  ..|..|:  |...|.||.|.|.....|..|  |.|   ...::..||.|:|  |..||
Worm   308 NLRRH--ARHHSGE--KVLACPFCARFFSRRDKLYDHCLRRTILMKNPEMEDPYLCKL--CQKRF 366

  Fly   304 YSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHI--NYHTLERTWSCKDCPKVCNSSTSLK 366
            .:.:.|.:|:.||  :.:.:||.|.|....:.||..|:  .:....:.:.|..|.|:..:.:.|.
Worm   367 GTEKALCMHVTRH--LVSLTCPLCSLGLGCRAELHRHLMTKHSRRSKDFKCDTCSKLFFTESELN 429

  Fly   367 KHIRAIHEKARDYACSYCEKKFATTDTRKYHEMTHTGEKNFE-----CHVCGKKFIQPSALRTH 425
            :|  |::.....|:|.:|.:||........|...|  ::||.     ||:|.:.:....||..|
Worm   430 RH--AVYHSDVMYSCKHCPEKFKWKKQLMKHMKEH--DENFNPSPYTCHLCDRTYTTGFALGRH 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10147	NP_001261477.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368
		zf-C2H2_8	199..287	CDD:292531	28/108 (26%)
		C2H2 Zn finger	199..221	CDD:275368	6/21 (29%)
		C2H2 Zn finger	230..253	CDD:275368	6/22 (27%)
		C2H2 Zn finger	264..284	CDD:275368	9/24 (38%)
		C2H2 Zn finger	294..316	CDD:275368	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	7/21 (33%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	6/17 (35%)
hinf-1	NP_493579.2	C2H2 Zn finger	299..316	CDD:275368	5/18 (28%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	359..379	CDD:275368	7/21 (33%)
		C2H2 Zn finger	385..406	CDD:275368	7/20 (35%)
		C2H2 Zn finger	415..435	CDD:275368	6/21 (29%)
		C2H2 Zn finger	442..462	CDD:275368	5/19 (26%)
		C2H2 Zn finger	473..494	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000