Protein Alignment CG10163 and PNLIPRP1

DIOPT Version :10

• Sequence 1: NP_648042.1
• Gene: CG10163 / 38728
• FlyBaseID: FBgn0035697
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_006220.1
• Gene: PNLIPRP1 / 5407
• HGNCID: 9156
• Length: 467
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 62/290 - (21%)
• Similarity: 111/290 - (38%)
• Gaps: 72/290 - (24%)

  Fly    73 LFQGINPSDARLHVMTITNQSVELPIKSISQIKDFDINPERKTLIYVNAF----------HTADS 127
            |:...||::.::           |.:...|.|:..:...:|||...::.|          .....
Human    58 LYTNENPNNFQI-----------LLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKK 111

  Fly   128 YFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLR-ALKDAGIAVQDI 191
            .|.|:|           :|.|.||:.|.....|....:::.|.|..|.::|. .|.:.......:
Human   112 LFEVEE-----------VNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKV 165

  Fly   192 TLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDP--ATMCRT-TDILVKQSVALRVVVLHGEGD 253
            .|.|||:||::|.     .|......:.::..:||  |:...| .::.:..|.|..|.|:|.:..
Human   166 HLIGHSLGAHVAG-----EAGSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAA 225

  Fly   254 V------FGVRVPLGHIDIYPNGIGYFPRRKLQPGCE----SKI---------------CSHMYP 293
            .      ||....:||:|.:|||      .:..|||:    |:|               |:|:..
Human   226 PLIPFLGFGTNQQMGHLDFFPNG------GESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRS 284

  Fly   294 FILFMEALIEGVMIPATKCESWAKFRQGDC 323
            :..::|:::......|..|.|:..|....|
Human   285 YKYYLESILNPDGFAAYPCTSYKSFESDKC 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10163	NP_648042.1	alpha/beta hydrolases	91..349	CDD:473884	59/272 (22%)
PNLIPRP1	NP_006220.1	Lipase	18..353	CDD:395099	62/290 (21%)
		PLAT_PL	356..467	CDD:238857