Protein Alignment CG10163 and PNLIP

DIOPT Version :10

• Sequence 1: NP_648042.1
• Gene: CG10163 / 38728
• FlyBaseID: FBgn0035697
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 76/343 - (22%)
• Similarity: 123/343 - (35%)
• Gaps: 100/343 - (29%)

  Fly    78 NPSDARLHVMTITN------QSVELPIKSISQIKDFDINPERKTLIYVNAF----------HTAD 126
            :|.|.....:..||      |.|.....|||. .:|..|  |||...::.|          :...
Human    47 SPKDVNTRFLLYTNENPNNFQEVAADSSSISG-SNFKTN--RKTRFIIHGFIDKGEENWLANVCK 108

  Fly   127 SYFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNG----YFVYKLLRALKDAGIA 187
            :.|.|:           .:|.|.||:.......|.....::.:.|    |||..|..|.   |.:
Human   109 NLFKVE-----------SVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAF---GYS 159

  Fly   188 VQDITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDPATMC-RTTDILVK--QSVALRVVVLH 249
            ..::.:.|||:||:.|...    .:.....:|::..:|||..| :.|..||:  .|.|..|.|:|
Human   160 PSNVHVIGHSLGAHAAGEA----GRRTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIH 220

  Fly   250 GEGDV------FGVRVPLGHIDIYPNGIGYFPRRKLQPGCESKI-------------------CS 289
            .:|..      ||:...:||:|.:|||      ....|||:..|                   |:
Human   221 TDGAPIVPNLGFGMSQVVGHLDFFPNG------GVEMPGCKKNILSQIVDIDGIWEGTRDFAACN 279

  Fly   290 HMYPFILFMEALIEGVMIPATKCESWAKFRQGDCNFQNTINIGLIYPANAKGLYFCMTQPNPPFT 354
            |:..:..:.::::.........|.|:..|....|           :|..:.|   |        .
Human   280 HLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKC-----------FPCPSGG---C--------P 322

  Fly   355 YMEHGLRYKARRPEKSSE 372
            .|.|   |..|.|.|:::
Human   323 QMGH---YADRYPGKTND 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10163	NP_648042.1	alpha/beta hydrolases	91..349	CDD:473884	67/305 (22%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:395099	76/343 (22%)
		PLAT_PL	355..465	CDD:238857