DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10163 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_648042.1	Gene:	CG10163 / 38728	FlyBaseID:	FBgn0035697	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_035258.2	Gene:	Pnliprp2 / 18947	MGIID:	1336202	Length:	482	Species:	Mus musculus

Alignment Length:	291	Identity:	64/291 - (21%)
Similarity:	116/291 - (39%)	Gaps:	68/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 NPSDARLHVMTITNQSVELPIKSISQIKDFDINP-----ERKTLIYVNAF----------HTADS 127
            :|.|.....:..||::.. ..:.||......||.     :|||...::.|          .....
Mouse    61 SPEDIDTRFLLYTNENPN-NYQIISATDPATINASNFQLDRKTRFIIHGFIDKGEEGWLLDMCKK 124

  Fly   128 YFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLRALK-DAGIAVQDI 191
            .|.|::           :|.|.||:.:.....|....::..|.|..:..|::.|. :.|.:.:::
Mouse   125 MFQVEK-----------VNCICVDWKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYSPENV 178

  Fly   192 TLAGHSVGANIAA-LGAQLFAKENKQLVGQLLAIDPATMC---RTTDILVKQSVALRVVVLHGEG 252
            .|.|||:|:::|. .|.:|     :..||::..:|||..|   ...::.:..|.|:.|.|:|.:.
Mouse   179 HLIGHSLGSHVAGEAGRRL-----EGHVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDS 238

  Fly   253 DV------FGVRVPLGHIDIYPNGIGYFPRRKLQPGCESKI-------------------CSHMY 292
            ..      ||:...:||:|.:|||      .|..|||:..|                   |:|:.
Mouse   239 APIIPYLGFGMSQKVGHLDFFPNG------GKEMPGCQKNILSTIVDINGIWEGTRNFAACNHLR 297

  Fly   293 PFILFMEALIEGVMIPATKCESWAKFRQGDC 323
            .:..:..:::.........|.|:.||:..||
Mouse   298 SYKYYASSILNPDGFLGYPCSSYEKFQHNDC 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10163	NP_648042.1	Abhydrolase	91..349	CDD:304388	61/278 (22%)
Pnliprp2	NP_035258.2	Lipase	31..367	CDD:278576	64/291 (22%)
		Pancreat_lipase_like	65..363	CDD:238363	62/287 (22%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	106..118		1/11 (9%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	270..292		1/21 (5%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910