DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10163 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_648042.1	Gene:	CG10163 / 38728	FlyBaseID:	FBgn0035697	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_061362.1	Gene:	Pnliprp1 / 18946	MGIID:	97723	Length:	473	Species:	Mus musculus

Alignment Length:	291	Identity:	63/291 - (21%)
Similarity:	113/291 - (38%)	Gaps:	69/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 NPSDARLHVMTITN------QSVELPIKSISQIKDFDINPERKTLIYVNAF----------HTAD 126
            :|.......:..||      |:::|...|..:..:|.:  .|||...::.|          ....
Mouse    48 SPEKINTRFLLYTNENPTAFQTLQLSDPSTIEASNFQV--ARKTRFIIHGFIDKGEENWVVDMCK 110

  Fly   127 SYFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLRAL-KDAGIAVQD 190
            :.|.|:|           :|.|.||:.:.....|....:::.|.|..|.:::..| ::...:...
Mouse   111 NMFQVEE-----------VNCICVDWKRGSQTTYTQAANNVRVVGAQVAQMIDILVRNFNYSASK 164

  Fly   191 ITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDP--ATMCRT-TDILVKQSVALRVVVLHGEG 252
            :.|.|||:||::|.     .|......:|::..:||  |....| .::.:..|.|..|.|:|.:.
Mouse   165 VHLIGHSLGAHVAG-----EAGSRTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDA 224

  Fly   253 DV------FGVRVPLGHIDIYPNGIGYFPRRKLQPGCE----SKI---------------CSHMY 292
            ..      ||....:||.|.:|||..|      .|||:    |:|               |:|:.
Mouse   225 APLIPFLGFGTNQMVGHFDFFPNGGQY------MPGCKKNALSQIVDIDGIWSGTRDFVACNHLR 283

  Fly   293 PFILFMEALIEGVMIPATKCESWAKFRQGDC 323
            .:..::|:::......|..|.|:..|....|
Mouse   284 SYKYYLESILNPDGFAAYPCASYRDFESNKC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10163	NP_648042.1	Abhydrolase	91..349	CDD:304388	61/278 (22%)
Pnliprp1	NP_061362.1	Lipase	18..353	CDD:278576	63/291 (22%)
		Pancreat_lipase_like	52..349	CDD:238363	62/287 (22%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840