DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10163 and LOC100331214

DIOPT Version :9

Sequence 1:	NP_648042.1	Gene:	CG10163 / 38728	FlyBaseID:	FBgn0035697	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_002666287.3	Gene:	LOC100331214 / 100331214	-ID:	-	Length:	501	Species:	Danio rerio

Alignment Length:	373	Identity:	87/373 - (23%)
Similarity:	143/373 - (38%)	Gaps:	105/373 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NIDSVQKHNVKLLSEQLNRGWRAFCDAPVDEGVMSLFQGINPSDARLHVMTITNQSVELPIKSIS 102
            ::..|:|.|||                         |...|||.....|..|.....|
Zfish    44 DLSDVKKLNVK-------------------------FSLRNPSQPDDDVCYIVRGKAE------- 76

  Fly   103 QIKDFDINPERKTLIYVNAFHTADSYFS-VQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHH 166
            .:...:.|...||::.::.:..:..:.| |::.:..|.|..:|.||||||:. |.||.:|.|
Zfish    77 TLSSCNFNHTSKTILVIHGWTVSGLFESWVEKLVAALYNREKDANVIVVDWL-DTAQDHYVV--- 137

  Fly   167 LSVNGYFVYKLLRALKD-----AGIAVQDITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDP 226
            .:.|...|.:.:....|     :.:.::::.|.|:|:||::|.....  ...||  :|::..:||
Zfish   138 AAQNTKMVGREIGLFIDWIEETSNVPLENLHLIGYSLGAHVAGFAGS--HTTNK--IGRITGLDP 198

  Fly   227 A---------------TMCRTTDIL---VKQSVALRVVVLHGEGDVFGVRVPLGHIDIYPNGIGY 273
            |               ......|:|   .:.|:.|.:          |:..|:||:|||||| |.
Zfish   199 AGPDFEGVHAHGRLSPDDAHFVDVLHTFTRGSLGLSI----------GIEQPVGHVDIYPNG-GS 252

  Fly   274 FPRRKLQPGCESK------------------ICSHMYPFILFMEALI-EGVMIPATKCESWAKFR 319
            |     ||||..:                  .|.|.....||:::|: |.....|..|.|...|.
Zfish   253 F-----QPGCNLRGALEKMASYGIFAINNAIRCEHERSIHLFIDSLLNEEAAGRAYSCGSNDMFD 312

  Fly   320 QGDC-----NFQNTINIGLIYPANAKGL-YFCMTQPNPPFTYMEHGLR 361
            :|.|     |..||:...:.....|:.: .|..|:.:.||....:.|:
Zfish   313 RGVCLQCRKNGCNTVGYDISKVRKARSVKMFTKTRGSMPFRVFHYQLK 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10163	NP_648042.1	Abhydrolase	91..349	CDD:304388	73/306 (24%)
LOC100331214	XP_002666287.3	lipo_lipase	47..487	CDD:132274	87/370 (24%)
		Pancreat_lipase_like	51..347	CDD:238363	81/351 (23%)
		PLAT_LPL	355..485	CDD:238856	1/6 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910