Protein Alignment Best2 and Best4

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: XP_001066317.1
• Gene: Best4 / 689103
• RGDID: 1596200
• Length: 454
• Species: Rattus norvegicus
• Alignment Length: 364
• Identity: 175/364 - (48%)
• Similarity: 245/364 - (67%)
• Gaps: 14/364 - (3%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            |||||..:|.. :.||.|..:|::||||:|||::||.:.:..||.|:|:.||..||:.|:.|:.:
  Rat     1 MTVSYTLKVAE-ARFGAFSGLLFRWRGSIYKLLYREFLLFCALYATLNITYRLLLTQEQKRIYAQ 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :..|..:.::.||:||||||||.|||.|||.||..:|.||.|...|||::    .|| :::|||:
  Rat    65 VARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASV----HGV-DQSGRLL 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVW 195
            ||.::||..||.|:.|:.:|.||.:||||.:|:||||.|.:.|.|.||:|  ||..:|||:|.||
  Rat   125 RRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESL--KSDFNKYWVPCVW 187

  Fly   196 ATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAAL 260
            .||:..:||:||.|..|..:..||.||:..|.:.|.|..||.:.:|||||||||:.:|::|..:|
  Rat   188 FTNLAAQARRDGRIRDDIALCLILEELNKYRAKCGMLFHYDWISIPLVYTQVVTIAVYSFFTLSL 252

  Fly   261 LGRQMLPNVLDRSGREDP---DLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDR 322
            :|||.:.:  |:.....|   |:|.||.|:|||.||.|||||||.|||||||||||.|.|.||||
  Rat   253 IGRQFVES--DKESSPAPWYLDMFVPLTTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNQLIDR 315

  Fly   323 HIKAAYMIVDEMHEEHPELLRDQYWECVVPKDLPYTVAS 361
            :.:.:.:.||:|::..|...:|.||:...|:. |||||:
  Rat   316 NFQVSLLSVDDMYQNLPPTEQDLYWDEARPQP-PYTVAT 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	156/313 (50%)
Best4	XP_001066317.1	Bestrophin	8..316	CDD:279411	156/317 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10736
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880