Protein Alignment Best2 and best2

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_988974.1
• Gene: best2 / 394571
• XenbaseID: XB-GENE-991642
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 206/509 - (40%)
• Similarity: 293/509 - (57%)
• Gaps: 52/509 - (10%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            |||:|...|.| :.||.|:|:|..||||:|||:::|.:|:..:|..:::||||.|.|.|:..|.|
 Frog     1 MTVTYTARVAN-ARFGGFYKLLLLWRGSIYKLLYKEFLAFFLMYLALSIIYRFFLNEEQKLYFDK 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :.:|....:..||:||||||||||||.|||.||..||:||.:...||..:..|     :|||||.
 Frog    65 VAIYCNNYANLIPVSFVLGFYVNLVVNRWWNQYLSLPFPDRVMCAISGTVHGS-----DETGRLY 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVW 195
            ||.:|||..|:.::.|:.:|....:||||..|:|:||.|...|.|.||  |.:|..:|||:|.||
 Frog   125 RRTLMRYCSLSGLLILRSVSTAAFKRFPTIDHVVEAGFMTRLERKKFE--NLQSSYNKYWVPCVW 187

  Fly   196 ATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAAL 260
            ..|:.::||.:|.|..||..:.::.||:..|...|.|..||.:.||||||||||:.:|::|:..|
 Frog   188 FCNLASQARSEGRIRDDHSFKMLMEELNTFRGNCGMLFHYDWISVPLVYTQVVTIAVYSFFLTCL 252

  Fly   261 LGRQMLPNVLDRSGREDPDLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDRHIK 325
            :|||.|.......|.| .||:.|:||:|||.||.|||||||.|||||||||||.|:|:||||:.:
 Frog   253 IGRQFLDPARGYPGHE-LDLYVPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFEINFLIDRNFQ 316

  Fly   326 AAYMIVDEMHEEHPELLRDQYWECVVPKDLPYTVASEHYRKDEP--KGSAEKYKVKKEDAMYANI 388
            .:.:.||||:.:.|.:.:|:||....|:. |||.|: .::|..|  :||.....:.|||..:
 Frog   317 VSMLAVDEMYSDVPPMEKDRYWNHSDPRP-PYTAAT-LFQKHMPSFQGSTFNMAIPKEDMQF--- 376

  Fly   389 MPGGGKRMLSD--DVYADYESVDTPMVERRKNNWLVRQLSRMG-SMRSQSTAYSSG-GMPFNR-- 447
                  :.|||  ::..|..:...|:        |.|.|..:| |..|.|.|.:|. ..|.:|
 Frog   377 ------QPLSDIEEMNEDTLTHPPPL--------LSRFLPGVGPSPLSSSAALASHFAAPGSRLT 427

  Fly   448 --NRLNSVYSS--------PESGLPLTILQQ----QQLQQAHQQQ--QAGSQPS 485
              .|..|.:||        |....|.:::..    ..:|:.|.::  ..|||.|
 Frog   428 LLRRSTSSFSSSSEFQCQEPVQDPPYSLVDSLGPGLNVQEGHTEELCNMGSQAS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	152/310 (49%)
best2	NP_988974.1	Bestrophin	8..316	CDD:395843	154/316 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110