Protein Alignment Best2 and best-16

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_001023344.2
• Gene: best-16 / 3565658
• WormBaseID: WBGene00020046
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 156/461 - (33%)
• Similarity: 242/461 - (52%)
• Gaps: 53/461 - (11%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLT-ESQQAI-F 63
            ||||||..| :.:.:..|.|:|.||:|||.|.:|.||:.::.||..|.:|.....: |::.|| .
 Worm     1 MTVSYALSV-SSARYSAFLKLLQKWKGSVLKAVWAELLVWIGLYTAIALIINLSFSPETKTAISI 64

  Fly    64 KKIRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGR 128
            :..||  ..|...:.:.|:|||:|.:||.||....:.:.:.:|:||.:|..|..|:..|     |
 Worm    65 EAARL--DDQLGILDIKFMLGFFVTIVVDRWKTILQNIGFIETVALSVSTIIRGSDDNV-----R 122

  Fly   129 LMRRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPL 193
            |.||:|:||:||:..:..:.||:||:|||||.:.|::||.:.|:|:...|  ..::..:|||:|:
 Worm   123 LARRSIIRYLVLSQAMVYRDISMRVRRRFPTMKSLMEAGFIFENELHELE--QTETGYNKYWVPI 185

  Fly   194 VWATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIA 258
            .|..:|:.|.::...|.:......:|..:.|.|.:|..|..:|.|.:|:.|.|:|.|.:..:|..
 Worm   186 NWCNSIVWRMQEQKYIEAPVSTNNVLNNIRDFRTQLENLCKFDWVPIPISYPQIVFLAVRIHFFF 250

  Fly   259 ALLGRQMLPNVLDRSGREDPDLFF---PLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLI 320
            .|..||.:|.      ..:..|::   ||.....|..|:||:||||.|:|||||||||.|.||:|
 Worm   251 TLFTRQYIPM------ETEEYLWYRHIPLIPATSFFLYLGWMKVAEALLNPFGEDDDDFEGNWVI 309

  Fly   321 DRHIKAAYMIVDEMHEEHPELLRDQYWECVVPKDLPY--TVASEHYRKDEP---KGSAEKYKVKK 380
            |::||....||||.|.|.|.|..||:.:   ||..|.  :|.:||     |   :|||....:..
 Worm   310 DKNIKTGMQIVDESHAECPILNIDQFSD---PKFGPMYPSVLAEH-----PHILQGSAADVVIPD 366

  Fly   381 EDAMYANIMPGGGKRMLSDDVYADYESVDTPMVERRKNNWLVRQLSRMGSM----RSQS-----T 436
            .|.          .:|:..|......|..:...::|:.:.:.|:..|:.:.    ||.|     |
 Worm   367 SDK----------SKMVHVDSKTSVASGASGSNDQRRESSIRRRFRRLSTRLKLGRSISHPKGQT 421

  Fly   437 AYSSGG 442
            ..|.||
 Worm   422 VKSPGG 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	113/315 (36%)
best-16	NP_001023344.2	Bestrophin	9..313	CDD:279411	114/319 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720