Protein Alignment Best2 and best-21

DIOPT Version :10

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_502846.2
• Gene: best-21 / 190674
• WormBaseID: WBGene00013520
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 378
• Identity: 135/378 - (35%)
• Similarity: 217/378 - (57%)
• Gaps: 29/378 - (7%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            |||:|..||.:.:|| .|.|:|..||||::|.:..||..::..:..:.::||:.:||.||..|:.
 Worm     1 MTVNYNQEVSSVNSF-TFVKLLMTWRGSIWKSVRWELTMWVIAFAVVQMVYRYLMTEDQQKFFEY 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            ..::...:...||::|:|||:|.:||.||...:..:.:.:.:||.:...:..:     :...:::
 Worm    65 SAIHLNVRLIHIPLTFMLGFFVTIVVDRWRSVFTNIGFIENVALSVGTLVAGT-----DHAAKVL 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPM-SKYWMPLV 194
            ||.|:||:||:.|:.|:.||:||:|||||.:.||..|.::..|:   |.:.:...| :|||:|..
 Worm   125 RRTIIRYLVLSQVLVLRDISMRVRRRFPTMESLVSGGFLYRDEL---ERMYKCDTMYNKYWLPTH 186

  Fly   195 WATNIINRAR-KDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIA 258
            ||..::::|. :...:.|...:.::|:.:.:.|:.:..|..||.|.:|:.|.|||.|.:..|||.
 Worm   187 WANQLVHKAMFETKNVDSVQSMNSVLMNIKEFRQSMEMLTKYDWVPIPIAYPQVVFLAVRVYFII 251

  Fly   259 ALLGRQMLPNVLDRSGREDPDLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDRH 323
            .|:.||.|.:......:.    ..|:.|:|||||:|||:||||.|:||.||||||.|.||||||:
 Worm   252 CLVSRQYLLSAPPTEAQS----IVPIMTILQFVFFVGWMKVAEALLNPLGEDDDDFECNWLIDRN 312

  Fly   324 IKAAYMIVDEMHEEHPELLRDQ--------YWECVVPKD----LPYTVA-SEH 363
            :.....|||..|:..|.|..|:        || |...|:    .|..|| |:|
 Worm   313 MSTGIEIVDTCHDSCPPLKLDEPDDESGTMYW-CHPTKNGSQAPPSAVAISQH 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..322	CDD:460047	111/310 (36%)
best-21	NP_502846.2	Bestrophin	8..311	CDD:460047	113/315 (36%)