Protein Alignment Best2 and best-2

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_502524.2
• Gene: best-2 / 182044
• WormBaseID: WBGene00007204
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 136/390 - (34%)
• Similarity: 230/390 - (58%)
• Gaps: 25/390 - (6%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            ||::|..|:....::. |:.:|::|:||::|.|:.|.:.:|..|..|:|:||..::|..|..|:.
 Worm     1 MTINYHKEIKTSHTWK-FFVLLFRWKGSIWKAIYMETIIFLICYGIISVVYRTAMSEPSQRTFES 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :..|..::...||:.|||||:|.:||.||.:.:|.:.:.|.:.|..:..:..:     :|...:.
 Worm    65 VIRYCDKRLSFIPLEFVLGFFVTIVVDRWTKLWRTVGFIDDVCLLANLYVRGT-----SEKAIIY 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPM---SKYWMP 192
            ||||.||..|..::..:.:|:|.:|||||.:.:|.||.|.:.|:.::.:...|:..   .|||:|
 Worm   125 RRNIARYCALTQLLVFRDVSMRTRRRFPTMETVVAAGFMSKDELDLYNSYTTKNNSRLGKKYWIP 189

  Fly   193 LVWATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFI 257
            ..||..:..:|||||.|.||:....:..|:...|..:..:..||.|.:||:|.|:|.|.:..||:
 Worm   190 ANWALCMTYKARKDGYIESDYFKAQMEGEIRTWRTNIEWVCNYDWVPLPLMYPQLVCLAVNLYFL 254

  Fly   258 AALLGRQMLPNVLDRSGREDP-DLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLID 321
            .:::.||:   |:::....|. |::||:.|.|||:||:|||||.||::|||||||||.|.|.|||
 Worm   255 VSIIARQL---VIEKHKMVDEVDVYFPVMTFLQFIFYMGWLKVIEVMLNPFGEDDDDFETNALID 316

  Fly   322 RHIKAAYMIVDEMHEEHPELLRDQYWECVVPKDLPYT-----VASEHYRKDEPKGSAEKYKVKKE 381
            |:|.....:||...:. ||||:||:::.|: ..|.|:     :::.||.     ||..:..::::
 Worm   317 RNITMGLKMVDNTMKT-PELLKDQFFDEVL-VSLLYSEESSQISNYHYH-----GSTSEVHLEQK 374

  Fly   382  381
             Worm   375  374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	116/314 (37%)
best-2	NP_502524.2	Bestrophin	8..319	CDD:279411	117/319 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I871
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720