Protein Alignment Best2 and best-14

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_505708.2
• Gene: best-14 / 179471
• WormBaseID: WBGene00009340
• Length: 405
• Species: Caenorhabditis elegans
• Alignment Length: 438
• Identity: 137/438 - (31%)
• Similarity: 240/438 - (54%)
• Gaps: 42/438 - (9%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            ||:||..|         |..::.:||||::|.:.::|:.:...||.:.....:.|.|..:..|..
 Worm     1 MTISYDEE---------FSSLMLRWRGSIWKAVLKDLIGFYIAYYIVLAFQWYLLDEKGKEYFTG 56

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            ..::....::.||:||:|||:|:|:|.|||||:..:.|||.:.:.:||.:|.:...|       :
 Worm    57 WIMWCEIGAQYIPLSFLLGFFVSLIVARWWEQFNCISWPDKMMIMVSACLPGNENMV-------V 114

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVW 195
            |:.|.|:..|...|....:|::..:||||.:|:|.:.||.|.|..::  :|..:|..|:::|::|
 Worm   115 RQTIARWSSLQAAIAWSGVSVKTLKRFPTERHMVASKLMTEEEYDLY--MNTDAPHGKWFIPILW 177

  Fly   196 ATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAAL 260
            ..|:|.:.::.|:|.|.. :..:|.::...|.....|..||.:.:||||||||.:..|.||...|
 Worm   178 IVNLIKKQKQKGIIDSIQ-MDMLLKQVYSYRDGFAMLFVYDWIKIPLVYTQVVAIATYGYFFICL 241

  Fly   261 LGRQMLPNVLDRSGREDPDLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDRHIK 325
            :|||  |.:..||..::..:.||:||..|.:||:|||||.:.|:|||||||||.|||:::||:..
 Worm   242 IGRQ--PKLDQRSMEKEITILFPIFTTFQMLFYLGWLKVGQYLMNPFGEDDDDFELNYVLDRNTA 304

  Fly   326 AAYMIVDEMHEEHPELLRDQYWECVVPKDLPYTVASEHYRKDEPKGSAEKYKVKKEDAMYANIMP 390
            .|:|:..|:.::.|.:     ...:||. :|:|.||...:...||.....:|:.:.:
 Worm   305 IAHMMASELSDQLPSI-----GAPMVPA-VPHTRASFKIQDVIPKSHLAGFKLSEAE-------- 355

  Fly   391 GGGKRMLSDDVYADYESV--DTPMVERRKNNWLVRQLSRMGSMRSQST 436
               .:::..:...::|.:  :|.:..|::...|||.|.:  ..|:.:|
 Worm   356 ---MKLIKPEDLEEHERLMEETKVTNRQRLGTLVRALEK--KSRTNAT 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	110/310 (35%)
best-14	NP_505708.2	Bestrophin	9..302	CDD:279411	109/304 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D279144at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820