Protein Alignment Best2 and best-1

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_502523.1
• Gene: best-1 / 178264
• WormBaseID: WBGene00007203
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 157/478 - (32%)
• Similarity: 261/478 - (54%)
• Gaps: 50/478 - (10%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            ||::|..|:.....: .|:.:|:||:||::|.::.|.:.:|..|..|:|||:..:.||.|..|:.
 Worm     1 MTINYHKEIMTSHPW-TFFLLLFKWKGSIWKAVYMETIIFLICYGIISVIYKTAMGESSQRTFES 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :..||.::...||:.|||||:|..||.||.:.|:.:.:.|.:.|..:..|..:     .|..|:.
 Worm    65 LVRYFDKRLSYIPLEFVLGFFVTTVVNRWTKLYQTIGFIDNVGLMANCYIRGA-----TEKARIY 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQK--SPM-SKYWMP 192
            |||||||..|..::..:.:|:|.:|||||.:.:|.||.|::.|::::.:.:.|  |.: :|||:|
 Worm   125 RRNIMRYCELVQILVFRDMSMRTRRRFPTMETVVAAGFMNKHELELYNSYDTKYNSKLGTKYWIP 189

  Fly   193 LVWATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFI 257
            ..||..:..:|||||.|.||:....:..|:...|..:..:..||.|.:||:|.|:|.|.:..||:
 Worm   190 ANWALCMTYKARKDGYIESDYFKAQMEGEIRTWRTNIEWVCNYDWVPLPLMYPQLVCLAVNLYFL 254

  Fly   258 AALLGRQMLPNVLDRSGREDP-DLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLID 321
            .:::.||:   |:::....|. |::||:.|.|||:||:|||||.:|::|||||||||.|.|.|||
 Worm   255 VSIIARQL---VIEKHKMVDEVDVYFPVMTFLQFIFYMGWLKVIDVMLNPFGEDDDDFETNALID 316

  Fly   322 RHIKAAYMIVDEMHEEHPELLRDQYWECVVPKDLPYTVASE-------HYRKDEPKGSAEKYKVK 379
            |:|....||.|..... |||.:|.:::.|   |:|...:.|       ||.     ||..:.:::
 Worm   317 RNITMGLMIADNPMST-PELRKDPFYDEV---DVPLLYSEESSNIPNHHYH-----GSVSEVRLE 372

  Fly   380 KEDAMYANIMP-----GGGKRMLS----DDVYADYESVDTPMVERRKNNWLVRQLSRMGSMRSQS 435
            ::......:||     ...:||:|    |:...|..:......:.|..||  |::|...|..:.
 Worm   373 QKGNAPVMMMPHSQSAANLRRMMSFKSVDEDEKDINAFSMSHDDARMRNW--REVSLDSSFLAD- 434

  Fly   436 TAYSSGGMPFNRNRLNSVYSSPE 458
                     .|.|:...:.::|:
 Worm   435 ---------LNENKEWKIPTNPQ 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	121/314 (39%)
best-1	NP_502523.1	Bestrophin	8..319	CDD:279411	122/319 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I871
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4777
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720