Protein Alignment Best2 and best-18

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_001255067.1
• Gene: best-18 / 176436
• WormBaseID: WBGene00011868
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 139/401 - (34%)
• Similarity: 222/401 - (55%)
• Gaps: 24/401 - (5%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            |||||...|.....: .|..::::|||||:..||.:...:|.||:.::.||||.|:..||.||.:
 Worm     1 MTVSYNQSVATSRPW-TFLALIFRWRGSVWSAIWIQYSVWLGLYFLVSAIYRFILSAYQQQIFVR 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :..|...:...:|:.::|||::..|::|:|..|.::.:.|.:|...:..|..     ::|..:..
 Worm    65 LVDYVNSRMSYVPLDWMLGFFIAGVLRRFWYLYDIIGFIDNIACSTATYIRG-----DSERAKQY 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVW 195
            ||||:||..|..|:..:.:|::.::||||...:..||.|...|...|:.:...  .:||::|..|
 Worm   125 RRNIIRYCELTQVLIFRDLSMKARKRFPTLDTVAAAGFMMPHEKANFDLIQYN--YNKYFLPFNW 187

  Fly   196 ATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAAL 260
            |..::..|||:|||..|:.|..|..::...|..|..:..||.|.:|::|..:|.|.::.||...:
 Worm   188 AWALVYNARKEGLIEGDYYVTVISEDIKKFRTGLAWVCNYDWVPLPIIYPTIVCLAVHMYFFVGI 252

  Fly   261 LGRQMLPNVLDRSGRE-DP---DLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLID 321
            |.||.:      .|.| ||   ||.||..|.:|||||:|||||.|.|:||:|||.||.|.|.|||
 Worm   253 LARQYV------KGSEIDPDMIDLVFPFMTSIQFVFYMGWLKVGEGLLNPWGEDPDDFETNMLID 311

  Fly   322 RHIKAAYMIVDEMHEEHPELLRDQYWECV-VPKDLPYTVASEHYRK-DEPKGSAEKYKVKKEDAM 384
            |::.....||||.:::.|.|.:|.:|:.. ||.   |:.||.|.:: .:.:||....|:.: ...
 Worm   312 RNLAMGLKIVDEGYDKTPRLEKDAFWDDTWVPL---YSEASAHEKRYHQRQGSLAHIKIGR-SVS 372

  Fly   385 YANIMPGGGKR 395
            ...::|..|:|
 Worm   373 QVRMVPRDGRR 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	113/314 (36%)
best-18	NP_001255067.1	Bestrophin	9..314	CDD:279411	114/318 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I871
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4777
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820