Protein Alignment Best2 and best-5

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_499142.2
• Gene: best-5 / 176367
• WormBaseID: WBGene00007404
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 134/381 - (35%)
• Similarity: 226/381 - (59%)
• Gaps: 22/381 - (5%)

  Fly    20 KILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKKIRLYFGQQSESIPMSFVLG 84
            ::::|||||:::.:::||:.::|.|..::|||||.||.||:.||::...|...:...:|::||||
 Worm    62 RMIFKWRGSLWQAVYKELIVWICAYSLVSVIYRFALTRSQKDIFERFGEYCDARMGYLPLNFVLG 126

  Fly    85 FYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLMRRNIMRYMVLAYVITLQRI 149
            |:.|::::||.:.|..|...|.:|||:||.:..:     ::..|.:||||:||.|::..:..:.|
 Worm   127 FFCNIIIRRWLKLYTSLGNIDNIALFVSAYVRGT-----DDRARQIRRNIIRYCVISQCLVFRDI 186

  Fly   150 SLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVWATNIINRARKDGLIASDHI 214
            .:.|:|||||.:.:..||:|...|::.|.::  ||...|||:...||..::|.|:.:..|..|:.
 Worm   187 HVGVRRRFPTLEAVAQAGIMLPHELEKFNSI--KSRYQKYWVSFNWALELLNVAKTEKSIDGDNA 249

  Fly   215 VQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAALLGRQMLPNVLDRSGREDPD 279
            ...|..|:|..|..|..:..||.|.:||:|.|:|.:.::|||...:..||...:. |...:.:.|
 Worm   250 RNAIAQEISKFRSALTTVSMYDWVPIPLMYPQLVNMAVHTYFFLCIFTRQFFISA-DAHNKTEVD 313

  Fly   280 LFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDRHIKAAYMIVDEMHEEHPELLRD 344
            |:.|..|:::|:||:||||||..|:||||||.||.:.|.||||::......||:.:::.||:..|
 Worm   314 LYIPFMTIIEFIFYMGWLKVAMELLNPFGEDADDFDCNLLIDRNLAIGLTSVDDAYDQLPEVKPD 378

  Fly   345 QY-WECVVPKDLPYTVASEHYRKDEPKGSAEKYK----VKKEDAMYANIMPGGGKR 395
            .: ...|.|.|...|.:.:::     .|||.:.:    :|||:    |.|...||:
 Worm   379 VFTGGSVKPLDSDDTRSLKYH-----FGSAAQMEEISYLKKEE----NKMIAAGKK 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	115/303 (38%)
best-5	NP_499142.2	Bestrophin	51..358	CDD:279411	115/303 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I871
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4777
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720