Protein Alignment Best2 and best-26

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_493478.1
• Gene: best-26 / 173291
• WormBaseID: WBGene00014103
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 441
• Identity: 140/441 - (31%)
• Similarity: 225/441 - (51%)
• Gaps: 61/441 - (13%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTES--QQAIF 63
            |||.|..:||.|::...|:||:.|.:|:::..|::||..:|.||:...||||..|.:|  |:.|.
 Worm     1 MTVPYYRDVPTGNALRNFFKIMLKRKGNLFTAIFKELCLFLGLYFLFMVIYRLVLPKSGGQREIR 65

  Fly    64 KKIRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAA-------IPNSNGG 121
            |.:......|..:||:.|:|||:|:.||.||.:..      |:||...|.|       .|||||.
 Worm    66 KIVENLLSHQEFTIPLEFLLGFFVSSVVDRWRKSL------DSLAYIESCAHAVVIGFPPNSNGS 124

  Fly   122 VNNETGRLMRRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPM 186
            ..|   .|:||.|:||:|::.::..:.|||:|:|||.....|..|.|::::|:.....|..|. .
 Worm   125 DKN---LLIRRTIIRYLVVSQILLYREISLKVRRRFKKLTILGKAKLLNQNEIDKLNKLECKH-Y 185

  Fly   187 SKYWMPLVWATNII-NRARKDGLIASDHIVQTIL-VELSDIRRRLGGLIGYDTVCVPLVYTQVVT 249
            ..|::|:.||.::| ::..|:.| |::.   ||| .::.:.:.:|..|...|.:.:||.|.|.|.
 Worm   186 DIYFLPISWALSLIEDKIDKENL-ANEF---TILWGQIKEWQTKLSLLRNCDYIPIPLAYPQAVF 246

  Fly   250 LVLYTYFIAALLGRQMLPNVLDRSGREDPDL-----FFPLFTVLQFVFYVGWLKVAEVLINPFGE 309
            |.:..||...:..||.|       .|.|..:     |||:.|..|::|.:||:||||:|:||.||
 Worm   247 LAVRCYFAVCVFTRQHL-------DRYDSKMHTWITFFPVLTTFQYIFMMGWMKVAEILLNPMGE 304

  Fly   310 DDDDIELNWLIDRHIKAAYMIVDEMHEEHPELLRDQYWECVVPKDL-PYTVASEHYRKDEPKGSA 373
            |:||.|||::||.::|....||..:...|.:|...:     :..|. ||
 Worm   305 DEDDFELNFIIDNNLKNGLDIVSGLCGNHRKLAEHE-----IENDCRPY---------------- 348

  Fly   374 EKYKVKKEDAMYANIMPGGGKRMLSDDVYADYESVDTPMVERRKNNWLVRQ 424
              |:..::|.......|...|.:.......:..|.|:|||.:.::...:|:
 Worm   349 --YQTNEQDRKKNRAPPESLKNVEFKSFTMEKASKDSPMVVKSESVCCLRR 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	115/326 (35%)
best-26	NP_493478.1	Bestrophin	15..319	CDD:279411	115/324 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820