Protein Alignment Best2 and best3

DIOPT Version :9

• Sequence 1: NP_729159.2
• Gene: Best2 / 38727
• FlyBaseID: FBgn0035696
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_001155224.1
• Gene: best3 / 100302039
• XenbaseID: XB-GENE-1194414
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 683
• Identity: 239/683 - (34%)
• Similarity: 339/683 - (49%)
• Gaps: 142/683 - (20%)

  Fly     1 MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKK 65
            |||:|:.:|.|.:.|| |.::|.|||||:|||::||.:.:..||.|::|||||.||:||:..|:|
 Frog     1 MTVTYSSKVANATFFG-FHRLLLKWRGSIYKLLYREFLLFTSLYTTLSVIYRFFLTDSQKRYFEK 64

  Fly    66 IRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLM 130
            :.:|..:.:|.||::|||||||.|||.|||.|:..|||||.|...||:   |.:|  .:|.|||:
 Frog    65 VSMYCDKYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISS---NVHG--RDEYGRLL 124

  Fly   131 RRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVW 195
            ||.:|||:.|..::..:.:|..|.:||||..|:|:||.|...|.|:|::|  |||..|||:|::|
 Frog   125 RRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTSDERKLFDSL--KSPHLKYWVPVIW 187

  Fly   196 ATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAAL 260
            ..|:.::||.:|.|.....:|.::.|::..|.....|.|||.|.:||||||||||.:||:|.|.:
 Frog   188 FGNLASKARSEGRIRDSIDLQMMMNEMNKFRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACI 252

  Fly   261 LGRQMLPNVLDRSGREDPDLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDDDIELNWLIDRHIK 325
            :|||.|.......| .|.||:.|:||:|||.||.|||||||.|||||||||||.|.||.|||:::
 Frog   253 IGRQFLDPKQAYPG-HDLDLYIPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQ 316

  Fly   326 AAYMIVDEMHEEHPELLRDQYWECVVPKDL--PYTVASEHYRKDEPKGSAEKYKVKKEDAMYANI 388
            .:.|.|||||...|::.||.||.   ..|:  |||:|:..|......||.  ..:...|:::
 Frog   317 VSLMAVDEMHMNLPKMNRDIYWN---DSDVRPPYTLAAADYCIPSFLGST--VHMGLPDSVF--- 373

  Fly   389 MPGGGKRMLSDDVYADYESVDTPMVERRKNNWLVRQLSRMGSMRSQSTAYSS-GGMPFNRNRLNS 452
                    |.:|...|   .|.|    |:.:.::|::.|..|:...|...|| ||.....:..::
 Frog   374 --------LREDWLLD---EDKP----RRQHSVLRRVKRFLSVHEHSPDSSSRGGYSRQGSDASN 423

  Fly   453 VYSSPESGLPLTILQQQQLQQAHQQQQAGSQPSKSSLYGKFVHRKSLRAQRQLIKQNSKLNGLNV 517
            ::.                            ||:.:..|.| |....||:.
 Frog   424 IFF----------------------------PSELNYSGSF-HDAPHRARH-------------- 445

  Fly   518 NVAKTRPRIPTPEVAKDGNTNPATSSVLMAPQQLSTTSAPPGMYPSSYAPDTLLHQESGQVLGTL 582
            :...|:.|..|     |.|:.|.|               |.|.
 Frog   446 HAFHTKRREST-----DKNSKPTT---------------PKGD---------------------- 468

  Fly   583 LLSPIKEMDSSSSNNTLIPGHPATAALAASMKEGFTPSSIPAATNITTLSFPFSVTSTGGETMPT 647
             ||.|:|...|.::.            .||...|.||.        ..|..|...||:.||||.|
 Frog   469 -LSTIREASRSDTSG------------RASTSNGLTPD--------IALKVPEVATSSSGETMTT 512

  Fly   648 GTLSILPISANAQLPTITTTASGYDPNDVITTI 680
            .. |.:|..:|:...:.|...||....|..|.:
 Frog   513 AH-SAVPPQSNSLTVSDTMECSGNYQCDTNTAV 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best2	NP_729159.2	Bestrophin	13..324	CDD:279411	156/310 (50%)
best3	NP_001155224.1	Bestrophin	8..316	CDD:395843	158/316 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110