Protein Alignment Mdr65 and ABCB26

DIOPT Version :10

• Sequence 1: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_177218.3
• Gene: ABCB26 / 843398
• AraportID: AT1G70610
• Length: 700
• Species: Arabidopsis thaliana
• Alignment Length: 610
• Identity: 197/610 - (32%)
• Similarity: 324/610 - (53%)
• Gaps: 48/610 - (7%)

  Fly   711 KP-NFFRTFSRILQL-AKQEWCY------LILGTISAVAVGFLYPAF--AVIFGEFYAALAEKDP 765
            || ..:|..||:.:| |:..|..      ||:..:|.:.:    |.|  |.||......:|...
plant   117 KPVTVWRALSRMWELVAEDRWVIFAAFSTLIVAALSEITI----PHFLTASIFSAQSGDIAVFH- 176

  Fly   766 EDALRRTAVLSWACLGLAFLTGL-VCFLQTYLFNYAGIWLTTRMRAMTFNAMVNQEVGWFDDENN 829
                |...:|...|:.....:|: .||     |..|.:.|..|||...::.::.|::.:||.:
plant   177 ----RNVKLLVTLCVTSGICSGIRGCF-----FGIANMILVKRMRETLYSTLLFQDISFFDSQ-- 230

  Fly   830 SVGALSARLSGEAVDIQGAIGYPLSGMIQALSNFISSVSVAMYYNWKLALLCLANCPIIVGSVIL 894
            :||.|::||..:...:...||..|:.:.:.:.....::...:..:|.|.|..|..|.|:...:.:
plant   231 TVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQGTGALIYLLILSWPLGLCTLVICCILAAVMFV 295

  Fly   895 EAKMMSNAVVREKQVIEEACRIATESITNIRTVAGLRREADVIREYTEEIQRV-EVLIRQKLRWR 958
            ............:::...|..:|.|:.:.:|||.....|....:.|...:||: ::.:||...:
plant   296 YGMYQKKTAKLIQEITASANEVAQETYSLMRTVRVYGTEKQEFKRYNHWLQRLADISLRQSAAY- 359

  Fly   959 GVLNSTMQASAFFAYAVALCYGGVLVSEGQLPFQDIIK---VSETLLYGSMMLAQSLAFTPAFSA 1020
            |:.|.:..........:|:..||:.:..||:..:.:.|   .||.|:|.:..:..:|:   :...
plant   360 GIWNWSFNTLYHATQIIAVLVGGLSILAGQITAEQLTKFLLYSEWLIYATWWVGDNLS---SLMQ 421

  Fly  1021 ALIAGHRLFQILDRKPKIQSPMGTIKNTLAKQLNLFEGVRYRGIQFRYPTRPDAKILNGLDLEVL 1085
            ::.|..::||::|.||   |.....|.|..::|.  ..:.:..:.|.||:|.:..::..:::.|.
plant   422 SVGASEKVFQMMDLKP---SDQFISKGTRLQRLT--GHIEFVDVSFSYPSRDEVAVVQNVNISVH 481

  Fly  1086 KGQTVALVGHSGCGKSTCVQLLQRYYDPDEGTIHIDHDDIQHDLTLDGVRTKLGIVSQEPTLFER 1150
            .|:.||:||.||.||||.|.||.:.|:|..|.|.:|...:: :|.:..:|.::|.|.|||.||..
plant   482 PGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLDGVPLK-ELDVKWLRQRIGYVGQEPKLFRT 545

  Fly  1151 SIAENIAYGDNRRSVSMVEIIAAAKSANAHSFIISLPNGYDTRMGARGTQLSGGQKQRIAIARAL 1215
            .|:.||.||.: |::|..:||:|||.|.||.||.:|||||:|.:.  ...||||||||||||||:
plant   546 DISSNIKYGCD-RNISQEDIISAAKQAYAHDFITALPNGYNTIVD--DDLLSGGQKQRIAIARAI 607

  Fly  1216 VRNPKILLLDEATSALDLQSEQLVQQAL----DTACSGRTCIVIAHRLSTVQNADVICVIQNGQV 1276
            :|:|:||:|||||||||.:||..|:..|    :.:.:.|:.|||||||||:|.||.|..:.:|:|
plant   608 LRDPRILILDEATSALDAESEHNVKGVLRSIGNDSATKRSVIVIAHRLSTIQAADRIVAMDSGRV 672

  Fly  1277 VEQGNHMQLISQGGIYAKLHKTQKD 1301
            ||.|:|.:|:|:.|:||:|.|.|.|
plant   673 VEMGSHKELLSKDGLYARLTKRQND 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr65	NP_476831.1	MdlB	118..641	CDD:440747
		MdlB	711..1299	CDD:440747	195/606 (32%)
ABCB26	NP_177218.3	MdlB	122..695	CDD:440747	193/601 (32%)