Protein Alignment Mdr65 and ABCB29

DIOPT Version :9

• Sequence 1: NP_476831.1
• Gene: Mdr65 / 38726
• FlyBaseID: FBgn0004513
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_196011.1
• Gene: ABCB29 / 830269
• AraportID: AT5G03910
• Length: 634
• Species: Arabidopsis thaliana
• Alignment Length: 627
• Identity: 181/627 - (28%)
• Similarity: 275/627 - (43%)
• Gaps: 111/627 - (17%)

  Fly    45 IGWLFFGFIMC-CIKALTLPAVVIIYSEFTSMLVDRAMQFGTSSNVHALPLFGGGKTLTNASREE 108
            :|||      | |:..::|..:|.....|||.|...|... |......|.|.|
plant    78 LGWL------CSCVSVVSLSQIVPRLGSFTSNLNANAASL-TKLKGECLVLAG------------ 123

  Fly   109 NNEALYDDSISYGILLTIASVVMF-----------ISGIFSVDVFNMVALRQVTRMRIKLF---S 159
                           |.:|.||.:           ::.::.:.||   |.|:|....::.|   :
plant   124 ---------------LVLAKVVAYYLQQAFLWEAALNTVYKIRVF---AYRRVLERELEFFEGGN 170

  Fly   160 SVIRQDIGWHDLASKQNFTQSMVDDVEKIRDGISEKVGHFVYLVVGFIITVAISFSY-------- 216
            .:...||.:...|.                   :.:|...:|.::..::..||..|.
plant   171 GISSGDIAYRITAE-------------------ASEVADTIYALLNTVVPSAIQISVMTAHMIVA 216

  Fly   217 GWKLTLAVSSYIPLVILLNYYVAKFQGKLTAREQESYAGAGNLAEEILSSIRTVVSFGGEKSEVQ 281
            ...|||..:..||.|.||..|:.....|::.:.|.:.|.......|:|.:|..|.:...|.||..
plant   217 SPALTLVSAMVIPSVALLIAYLGDRLRKISRKAQIASAQLSTYLNEVLPAILFVKANNAEISESV 281

  Fly   282 RYENFLVPAR-------KASQWKGAFSGLSDAVLKSMLYLSCAGAFWYGVNLIIDDRNVENKEYT 339
            |::.|   ||       |..:.|.....:...:....|.:.|.||      :|:...::.:....
plant   282 RFQRF---ARADLDERFKKKKMKSLIPQIVQVMYLGSLSIFCVGA------VILAGSSLSSSAIV 337

  Fly   340 PAILMIAFFGIIVGADNIARTAPFLESFATARGCATNLFKVIDLTSKIDPLSTDGKLLNYGLRGD 404
            ..:..:||.     .|.:...................||.:..|.||:  :.....:....:.|:
plant   338 SFVASLAFL-----IDPVQDLGKAYNELKQGEPAIERLFDLTSLESKV--IERPEAIQLEKVAGE 395

  Fly   405 VEFQDVFFRYPSRPEVIVHRGLNIRIRAGQTVALVGSSGCGKSTCVQLLQRFYDPVFGSVLLDDL 469
            ||..|:.|:|......::. |||:.|:||:||||||.||.||:|.::||.|.|:|..||:::|.:
plant   396 VELCDISFKYDENMLPVLD-GLNLHIKAGETVALVGPSGGGKTTLIKLLLRLYEPSSGSIIIDKI 459

  Fly   470 DIRKYNIQWLRSNIAVVGQEPVLFLGTIAQNISYG--KPGATQKEIEAAATQAGAHEFITNLPES 532
            ||:...::.||.::.:|.|:..||.||||.||.|.  ..|...|.:|.||..|.|.|||.||||.
plant   460 DIKDIKLESLRKHVGLVSQDTTLFSGTIADNIGYRDLTTGIDMKRVELAAKTANADEFIRNLPEG 524

  Fly   533 YRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRTTIV 597
            |.:.:|.|||.||||||||:||||||.|...||:|||||||||..||..|::||:...:..|.||
plant   525 YNTGVGPRGSSLSGGQKQRLAIARALYQKSSILILDEATSALDSLSELLVREALERVMQDHTVIV 589

  Fly   598 VSHRLSAIRGADKIVFIHDGKVLE------EGSHDDLMALEG 633
            ::|||..:..|.::..:..||:.|      ..:|.|.:...|
plant   590 IAHRLETVMMAQRVFLVERGKLKELNRSSLLSTHKDSLTSAG 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr65	NP_476831.1	PTZ00265	91..1300	CDD:240339	168/580 (29%)
		ABC_membrane	108..354	CDD:279056	50/274 (18%)
		ABC_MTABC3_MDL1_MDL2	405..642	CDD:213216	108/237 (46%)
		ABC_membrane	736..1006	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1059..1299	CDD:213216
ABCB29	NP_196011.1	MdlB	77..613	CDD:224055	177/607 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810